The median (Q1, Q3) N-terminal pro-B type natriuretic peptide and high sensitivity cardiac troponin T were 71 (35, 135) ng/L and 9 [6, 12] ng/L. The most common echocardiographic abnormalities were reduced global longitudinal strain in 25.3% and impaired diastolic relaxation in 17.7%. ...
Cardiac deathHypertrophic cardiomyopathy is one of the most common inherited cardiac disorders, with a prevalence of 1:500 in the general population. We have recently reported a severe neonatal hypertrophic cardiomyopathy caused by a novel homozygous splice site c.3330 + 2 T > G mutation in the ...
Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is associated with sudden cardiac death. This disease has a prevalence of less than 1 per 500 and a mortality rate that is four-fold higher in young adults than the general US population1,2,3,4,5,6. Most treatments (e.g...
Hypertrophic cardiomyopathy is the most prevalent inherited cardiac disease in humans with an estimated incidence of up to 1:500 (0.2%) in the general population5. Despite the prevalence of this disease, advancements in therapeutic options are severely lacking and treatment is based on empirical ther...
Cardiac magnetic resonance imaging may help to distinguish constrictive pericarditis from restrictive cardiomyopathy. Definitive diagnosis is made by direct inspection of the pericardium and pericardial biopsy; however, the risks of sternotomy are high in patients with low cardiac output secondary to restric...
Echocardiography is the most frequently used method to diagnose LVNC. The echocardiographic diagnostic criteria for LVNC are well established and it includes the demonstration of a thickened myocardium exhibiting a noncompacted endocardial layer and a compacted epicardial layer. The ratio of the ...
Cardiac sarcoidosis: diagnosis and management. Cardiac sarcoidosis is one of the most serious and unpredictable aspects of this disease state. Heart involvement frequently presents with arrhythmias or c... SW Dubrey,R Sharma,R Underwood,... - 《Postgraduate Medical Journal》 被引量: 17发表: 2015...
including the general availability of cardiac transplantation and better medical treatment, clinical outcome following the onset of symptoms has not substantially changed. Mortality remains high, the disease is progressive and unrelenting, and disability and morbidity are among the highest of any disease ...
Cardiovascular magnetic resonance (CMR) is one of the most popular medical imaging modalities to quantify the LV phenotypes due to its noninvasive and versatile nature10. However, the highly variable cardiac structures across different subjects and quantification tasks of small targets pose the biggest...
Cardiac amyloidosis is a specific cause of HF that is associated with high morbidity and mortality, and is often misdiagnosed as other, more common forms of HF and cardiac disease21. Disease-modifying treatments are now available for both of the most common types of cardiac amyloidosis (ATTR an...