Left atrial appendage occlusion devices have been developed as an alternative to these agents, aiming to avoid issues around consistency of anti-coagulation, bleeding risk, and drug-related side effects. The best evidence is available for Boston Scientific's Watchman device. The safety and effectivene...
Transcatheter PFO closure is recommended in patients fulfilling all the following criteria: age of 16 to 60 years; recent (less than or equal to 6 months) ischemic stroke; PFO associated with atrial septal aneurysm (greater than 10 mm) or with a right-to-left shunt of greater than 20 micro...
e–g Line plots showing the enrichment of stage-, organ-, tissue- and cell-type- eQTLs in various GWAS traits: e pulse pressure; f pulse rate; and g atrial fibrillation (ICD10 code: I48). Enrichment is plotted as the log (odds ratio) (Y axis) over all PP-H4 thresholds (0.05 to...
further treatment options include advanced heart failure therapies and consideration forheart transplant. Other factors that could lead to SCD despite ICD implants includeventricular arrhythmias, which fall under the detection limit of the device, and very rarely failure of the ICD in detecting thearrhyt...
As a preventive device for SCD, an implantable cardioverter-defibrillator (ICD) is the only applicable in a special high-risk group that unfortunately it seems to be ineffective even among them4. However, there is increased knowledge about the role of established traditional risk factors in the ...
Intercalated discs (ICDs) serve as conduits for communication and signalling between CMs. Mutations or changes in protein expression associated with the ICD complex can contribute to various heart diseases, including arrhythmogenic right ventricular cardiomyopathy, dilated cardiomyopathy and cardiomyopathic atr...
View all issues Partner journals Journal of Cardiac Failure - Intersections Open access Journal of Cardiac Failure - Intersections is an Open Access journal with a focus on heart failure and its various intersections with other disciplines and specialties within the broader cardiovascular community. Jou...
At the end of the periodic follow-up, FE had normalized in ten patients, allowing them to avoid ICD. Only 10 of the 26 participants with WCD had a proven indication for final implantation. There were no fatalities or problems in any of the patients. 展开 ...
10 Although the present finding has not been reported previously in ACS, similar results were reported in a poststroke depression cohort; 12-week antidepressant treatment allocation was associated with improved survival over a 9-year follow-up.28 Several issues should be considered in the ...
Subjects were adults (aged 18 years or older), who had been treated with an ICD regardless of type or indication. Two review authors independently extracted data and assessed risk of bias. The primary outcomes were all-cause mortality, serious AEs and health-related QOL. The secondary outcomes...