Understand and learn what is cardiac cycle. Get to know more about the function of the cardiac cycle, the cardiac cycle phases, and the...
CF-cardiac fibroblasts, CM-cardiomyocytes, EC-endocardium cells, and PE-pericardial cells. Cardiac lineage cell-clusters did not further sub-cluster in cell cycle analysis. In agreement with the observation from bulk-RNA-seq data (Fig.1f, g), allele-specific scRNA-seq analysis confirmed that the...
Completed libraries were pooled and then sequenced with a NextSeq Mid Output 300 cycle flow cell on the NextSeq 500 to produce 2 × 150 bp reads. Several approaches were taken to account for potential PCR mutation and nuclear mitochondrial DNA segments (NUMTs). On the former, the LoFREQ* ...
(Accumulated deficit model) FTS-5 FTS-3 FI-35 SHARE-FI CFS GFST Criteria ≧3 of the following components of the hypothesized cycle of frailty: Shrinking/weight loss, Weakness, Poor endurance and energy, Slowness, Low physical activity level 70 items including ADLs, psychosocial risk factors, ...
(RRG rats)42 were obtained from the platform transgenic rats immunophenomic (TRIP; Nantes, France) and housed in a controlled environment (temperature 21 ± 1°C, 12 h light/dark cycle) in the specific pathogen-free animal facilities at the l’Institut de Recherche en Santé de l’...
The acetyl-CoA is consumed by the tricarboxylic acid (TCA) cycle, which couples to ATP synthesis through the electron transport chain. Interestingly, PPARα target genes harboring a PPRE in their promoter regions are mainly found in the upstream metabolic pathway, including those involved in fatty...
J. (2002). Cardiomyocyte cell cycle regulation. Circulation Research, 90, 1044–1054. PubMed CAS Google Scholar Hodgson, D. M., Behfar, A., Zingman, L. V., et al. (2004). Stable benefit of embryonic stem cell therapy in myocardial infarction. American Journal of Physiology. Heart ...
This, along with a consistently low level of Ki-67 staining, a marker of an active cell cycle state, demonstrates an inherently low level of both cell proliferation and loss of cell viability in untreated microtissues (Fig. 1B and C). Moreover, no differences were observed in cellular ...
All the animals were housed in an environment with temperature of 22 ± 1 °C, a relative humidity of 50 ± 1% and a light/dark cycle of 12/12 h. All animal studies (including the rats euthanasia procedure) were done in compliance with the regulations and guidelines of the...
and prompts the user to enter any information which could not be downloaded through such an interrogation process. The program continues to cycle through steps53,54and55until all of the information is correct and the user enters a command indicating the information is correct. When the programmer...