Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely ...
Cardiac amyloidosis or amyloid cardiomyopathy (ACM), commonly resulting from extracellular deposition of amyloid fibrils consisted of misfolded immunoglobulin light chain (AL) or transthyretin (TTR) protein, is an underestimated cause of heart failure and cardiac arrhythmias. Among the three types of ...
Amyloidosis, an infiltrative disease characterized by deposition of high molecular weight insoluble protein has a low detection rate and poor prognosis with congestive heart failure being the most common cause of death. Although definitive diagnosis is based on endomyocardial biopsy, this is rarely ...
Despite advances in treatment, the prognosis for patients with amyloidosis is still poor and depends on the underlying disease type. Herein, we present new insights and recent advances in cardiovascular amyloidosis. 展开 关键词:amyloidasis cardiomyopathy ...
Amyloidosis is an uncommon systemic disease characterized by deposition of insoluble fibrillar protein in different organs and the prognosis is poor if the heart is involved. Experience with management of cardiac amyloidosis is difficult because of its rare occurrence, late presentation and ineffective tre...
We are reporting a case of cardiac amyloidosis with an initial presentation of CHF in which the patient survived for more than 9 years. The prognosis most likely depends on the period of disease remission (i.e., negative serum and urine immunoelectrophoresis), which, in turn, depends on ...
cardiac amyloidosis and helps decide the treatment modality and determining disease prognosis; it further emphasizes the need for an interprofessional team to diagnose and manage cardiac amyloidosis, including cardiologists, cardiovascular imaging specialists, heart and transplant specialists, and hematologists...
T. et al. Characterization and localization of the Huntington disease gene product. Hum. Mol. Genet. 2, 2069–2073 (1993). CAS PubMed Google Scholar Melkani, G. C. et al. Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress ...
Cardiac amyloid deposition, causing an infiltrative/restrictive cardiomyopathy, is a frequent feature of amyloidosis and a major determinant of survival. It may be the presenting feature of the disease or may be identified while investigating a patient presenting with other organ involvement. The need ...
Cardiac amyloidosis is prevalent in older patients with aortic stenosis and carries worse prognosis J Cardiovasc Magn Reson, 19 (2017), p. 98 Google Scholar 4 C. Nitsche, S. Aschauer, A.A. Kammerlander, et al. Light-chain and transthyretin cardiac amyloidosis in severe aortic stenosis: prev...