In the initial survey, participants self-reported information on age, sex, ethnic background, blood pressure, blood lipids, physical activity, Townsend Deprivation Index (TDI), chronic medical conditions, medication use and smoking and drinking habits. The TDI, which serves as an indicator of socio...
Ethnic, and population differences, may drive risk of mortality. There was significant heterogeneity identified in our meta-analysis and therefore our conclusions should be interpreted with caution. Unexplained heterogeneity in our analysis may originate from the variable SHR cut offs across the studies,...
The IDF definition incorporates ethnicity by providing different criteria for the MS in different ethnic groups [4]. Moreover, the IDF definition is the most updated and globally accepted definition for MS [4]. Nevertheless, this study had limitations. The findings apply mainly to Malaysian men ...
An overview of methods used to derive the metabolic syndrome score Several large-scale epidemiological studies that either focus on cardiovascular health or include CVD risk factors in children and adolescents have used various approaches to calculate a metabolic syndrome score (Table1). As shown in ...
Jose L. Flores‑Guerrero1, Hiddo J. L. Heerspink2, Margery A. Connelly3, Stephan J. L. Bakker1 and Robin P. F. Dullaart1 Abstract Background: Triglyceride-rich lipoproteins particles (TRLP) and low density lipoprotein particles (LDLP) vary in...
Background The binary diagnosis of Metabolic Syndrome(MetS) fails to accurately evaluate its severity, and the association between MetS severity and frailty progression remains inadequately elucidated. This study aims to clarify the relationship between the severity of MetS and the progression of frailty...
Background Helicobacter pylori (H. pylori), a widely prevalent pathogen that can be cured through relatively simple medical methods, is thought to be potentially associated with the risk of cardiovascular diseases (CVD), although controversy remains. Currently, it is unclear whether the triglyceride-...
Background Stress cardiovascular magnetic resonance (CMR) to screen for silent myocardial ischaemia in asymptomatic high risk patients with type 2 diabetes mellitus (DM) has never been performed, and its effectiveness is unknown. Our aim was to determine the feasibility of a screening programme using...
Background Patients with low-to-normal body mass index (BMI; < 25.0 kg/m2) were underrepresented in major randomized controlled trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors for type 2 diabetes. The present study aims to investigate the effectiveness of SGLT2 inhibitors for car...
All subjects were native to Malaysia and were males to avoid confounding effect of gender. The ages for all subjects were restricted to 40-70 years old because individuals with 40-70 years old contribute the majority cases of T2DM and MS. Subjects comprised three primary ethnic groups which wer...