The synthesis can also be conducted by derivatising the acid as acid halogenide and then effecting the condensation in the presence of a proton acceptor such as triethylamine, in conditions similar to those described above. In the case of formula (I) compounds in which Ar is an aromatic ...
5. The method of making the 7-(4-((5-(3-bromobenzylideneamino)-2-thioxo-1,3,4-thiadiazol-3(2H)-yl)methyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound of claim 4, wherein the reaction mixture is stirred at room temperature for at leas...
Bayesian mixed-effects logistic regression models, incorporating farm and county as arbitrary effects, were used to research associations between Toxoplasma test results and prospective risk aspects. A complete of 930 serum examples from 62 pig farms had been gathered and tested. A complete herd preval...
a major portion of the active substance is delivered to or within each target cell, avoiding undesirable secretion of phosphonocarboxylic acid by the kidneys or cleavage of the conjugate in the liver. As already mentioned, these cells are, in particular, physiologically...
8962660 Oxabicyclo [2.2.2] acid GPR120 modulators 2015-02-24 Zhang et al. 6011155 N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV 2000-01-04 Villhauer 6008220 Aromatic keto-acids and their derivatives as ...