ayou can eat some you can eat some[translate] aFOLDERS 文件夹[translate] asiting 选址[translate] aThe most original expressions of pain, was actually not feeling. 痛苦最原始的表示,实际上没有感觉。[translate] acarboxylic acid binding 羧酸捆绑[translate]...
Carboxylic acid derivatives inhibiting the binding of integrins to receptors thereofThe invention relates to a method for the inhibition of the binding of alpha4beta1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this ...
Although the introduction ofcarboxylic acidgroups on oxidizedSisurfaces can be directly achieved using molecules such as N-(trimethoxysilylpropyl) ethylene-diaminetriacetic acid or carboxyethylsilanetriolsodiumsalt, only a few examples have been described in the literature (Zlatanovic et al., 2009;Duval...
Surface carboxylic acid groups allow covalent amide bond formation to proteins, peptides via primary amino- or sulphydryl groups. Rapid binding chemistry, activation through carbodimide is required.
Carboxylic acid groups are then introduced on the surface of the beads. The small 1 μm Dynabeads MyOne™ Carboxylic Acid have hydrophilic surface, which ensures low non-specific binding, excellent dispersion abilities and easy handling in a wide variety ...
2). This effect is attributed to the fact that the strong zinc(II) affinity of hydroxamic acid group is the main determinant of the overall binding energy, in contrast with carboxylates where the binding energy relies to a bigger extent on specific interactions with the specificity pockets. ...
Binding constants for benzoic acid, its monosubstituted derivatives, and pyridine-carboxylic acids with bovine serum albumin were evaluated spectrophotometrically by utilizing the competition with 2-(4'-hydroxyphenylazo) benzoic acid (HABA). A modified Langmuir-type equation which quantitatively represented ...
be used to modify proteins, peptides and other materials via amino or other acid reactive chemical groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces...
Chemical structures of the tricarboxylic acid tectons that form HOFs. He names of the resultant HOFs are also presented at the bottom Full size image It is well known that 1 gives nonporous C2/c crystals composed of interpenetrated hcb undulated networks connected through dimerized carboxy groups....
SUBSTANCE: invention provides novel carboxylic acid derivatives having general formula I: (I) and containing heterocyclic moieties. Compound possess biological activity, in particular they inhibit binding of endothelin to receptors and can be used for treatment of hypertension, myocardial infarction, renal...