The process uses a reaction medium for the carbonylation that includes: (1) a rhodium catalyst, (2) an organic halide corresponding to said alcohol, (3) an ester of the alcohol and the carboxylic acid, (4) the carboxylic acid, optionally (5) water, a haloid acid, an inorganic halogen ...
With the goal to describe a wide variety of organic compounds found in atmospheric aerosols, we extend here the parameterization of AIOMFAC to include the functional groups carboxyl, hydroxyl, ketone, aldehyde, ether, ester, alkenyl, alkyl, aromatic carbon-alcohol, and aromatic hydrocarbon. ...
To gain more mechanistic insight into this transformation, we conducted several control experiments. As silyl enol ether1Acan be prepared easily from ketone1aand TMSCl in the presence of base, we wondered whether it might act as the reaction intermediate. However, we failed to detect1Aat differen...
25.The method according to claim 21, wherein the functionalized product is an ester selected from the group consisting of ethyl acetate, ethyl formate, ethyl isovalerate, isobutyl acetate, propyl isobutyrate, ethyl acetate, benzyl acetate, methyl phenylacetate, and combinations thereof. ...
Two more examples of reversing the polarity of a substituent is reduction of the nitro group and Baeyer-Villiger oxidation of a ketone to an ester. We’ll cover those next! Notes Related Articles More Reactions on the Aromatic Sidechain: Reduction of Nitro Groups and the Baeyer Villiger ...
In fact, as shown in Scheme 5, (section a), the formation of the above alkene can be easily understood in terms of a preliminary addition of the catalyst to the ester carbonyl (in spite of its lower reactivity with respect to aldehydes and ketones), followed by quaternization of the alkox...
13. A method of preparing a compound corresponding to formula I: wherein R1 is hydrogen or a group forming a biolabile ester, R2 is hydrogen, C1-4-alkyl or C1-4-hydroxyalkyl, the hydroxyl group of which is optionally esterified with C2-4-alkanoyl or an amino acid residue, and R3 is ...
Notably, the carbonyl–olefin metathesis of olefinic ketone 17, featuring α-oxygenation, leads to the formation of cyclic ketone 19d via the isomerization of the cyclic enol ether intermediate, facilitated by 20 (1.0 equiv). Interestingly, 19e bearing an ester functional group could be obtained ...
CONTROLS Lithium and magnesium are very electropositive metals. The Li-C or Mg-C bonds in organolithium or organomagnesium reagents are highly polarized towards carbon. Red represents areas which are electron rich, blue represents areas that are electron poor ...
The Cr2O72-ion (Cr VI) forms HCrO4–in acidic aqueous solution, which can eliminate a molecule of water to give the reagent CrO3. This then oxidises alcohols to a aldehydes and ketones via the chromate ester intermediate. The reduced chromium Cr (IV) can undergo series of reactions bri...