Carbidopa(MK-486) is a drug given to people with Parkinson's disease in order to inhibit peripheralmetabolismoflevodopa. Carbidopa inhibits aromatic-L-amino-acid decarboxylase (DOPA Decarboxylase or DDC), an enzyme important in the biosynthesis of L-tryptophan toserotoninand in the biosynthesis ofL...
It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA. 靶点活性 Aromatic-L-amino-acid decarboxylase:29 μM 别名 卡比多巴, Lodosyn, (S)-(-)-Carbidopa 化学信息 分子量 226.23 分子式 C10H14N2O4 CAS No. 28860-95-9 Smiles [C@@](CC1=CC(O)=C(O)C=C1)(C(O)...
Anti-β-Amyloid, Plaque Neutralizing Antibody BACE1, His-Tag (Human) Recombinant Cereblon/DDB1/Cul4A/Rbx1 Complex Recombinant Levodopa ● Related Services Immunotherapy Screening Services Product Info Storage and Usage Citations Purity ≥98% Supplied As Solid Formula C10H14N2O4 MW 226 Da Solubi...
Levodopa, USP an aromatic amino acid, is a white, crystalline compound, slightly soluble in water with a molecular weight of 197.19. It is designated chemically as (-)-L-α-amino-β-(3,4-dihydroxybenzene) propanoic acid. Its empirical formula is C9H11NO4, and its structural formula is: ...
The combination of carbidopa/levodopa enhances the bioavailability of carbidopa and levodopa. It?is also used in combination with 5-HTP, a naturally occurring amino acid which is a precursor to the neurotransmitter serotonin and an intermediate in tryptophan metabolism. People can use the following ...
Empirical Formula【经验(实验)分子式】 C10H14N2O4· H2O Molecular weight 244.24 MDL number MFCD00889211 PubChem Substance ID【PubChem化学物质编号】 329823533 NACRES NA.24 General description【一般描述】 Carbidopa is a peripheral decarboxylase inhibitor which is often formulated with levodopa for the ...
The present disclosure provides a pharmaceutical composition comprising (a) an improved pharmaceutical composition comprising a levodopa active agent and a carbidopa active agent, (b) a method of making the pharmaceutical composition, and (c) administering to the subject of Parkinson's disease said ...
Published 2017 Nov 6. [2]. Fermaglich J. Treatment of Parkinson’s disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa. Med Ann Dist Columbia. 1974;43(12):587-591. 所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务...
entacapone/carbidopa+entacapone+levodopa information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.
Treatment of Parkinson’s disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa. Med Ann Dist Columbia. 1974;43(12):587-591. [3]. Gilbert JA, et al. The aromatic-L-amino acid decarboxylase inhibitor carbidopa is selectively cytotoxic to human pulmonary carcinoid and small ...