https://www.nature.com/articles/s41591-023-02785-8 [3]Zhang X,et al.Cytokine release syndrome after modified CAR-NK therapy in an advanced non-small cell lung cancer patient: a case report[J]. Cell Transplantation, 2022, 31: 09636897221094244.https://journals.sagepub.com/doi/full/10.1177...
[2]Sauter C S,et al.A Phase 1 Study of NKX101, a Chimeric Antigen Receptor Natural Killer (CAR-NK) Cell Therapy, with Fludarabine and Cytarabine in Patients with Acute Myeloid Leukemia[J].Blood,2023,142:2097.https://ash.confex.com/ash/2023/webprogram/Paper173582.html [3]Wang W,et a...
参考资料 [1]Zhang X,et al.Cytokine release syndrome after modified CAR-NK therapy in an advanced non-small cell lung cancer patient: a case report[J]. Cell Transplantation,2022,31:09636897221094244. https://journals.sage...
Front Oncol. 2024 May 28;14:1390006. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165017/ [3]Zhang X,et al.Cytokine release syndrome after modified CAR-NK therapy in an advanced non-small cell lung cancer patient:...
CAR-NK细胞疗法作为抗癌领域的新兴疗法，被业内寄予厚望，但目前仍在临床试验阶段。虽然部分临床试验取得了可观的疗效，但仍具有改善的空间。随着临床研究的不断深入，CAR-NK细胞疗法将会是一个有效且安全的治疗方案。参考资料 1.Advances in CAR-NK cell therapy for lung cancer: is it a better choice in the ...
[5]Yao P,et al.The development and application of chimeric antigen receptor natural killer (CAR-NK) cells for cancer therapy: current state, challenges and emerging therapeutic advances[J]. Experimental Hematology & Oncology, 2024, 13(1): 1-27.https://ehoonline.biomedcentral.com/articles/10....
[1]Li L,et al.Loss of linkbolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering[J]. Science Advances, 2023, 9(30): eadd6997.https://www.science.org/doi/10.1126/sciadv.add6997 [2]Liu S,et al.Harnessing natural killer cells to ...
近日，中国科学院院士、免疫学家曹雪涛团队在国际期刊《Signal Transduction and Targeted Therapy》上发表突破性研究，揭示了一种新型 CAR-NK细胞疗法，通过Neo-2/15 技术增强 CAR-NK 细胞的存活率和杀伤力，使其在实体瘤治疗中展现出前所未有的潜力。这项研究标志着 CAR-NK 细胞疗法进入了实体瘤精准治疗的新阶段...
多数转移灶消失！NK细胞疗法在实体瘤具有显著疗效 除此之外，NK细胞疗法在实体瘤方面如胃癌、肝癌、肺癌等领域也取得了显著的成绩。2023年8月，一篇题为《Investigation of the efficacy and feasibility of combined therapy of PD 1﹏hanced exogenous peripatetic adoptive natural killer (NK) cells in combination ...
2.https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(19)30097-8?3.https://journals.lww.com/cancerjournal/fulltext/2020/16020/robo1_specific_chimeric_antige 特别声明 本文旨在介绍CAR-NK细胞疗法在癌症及免疫相关疾病中的应用与进展。所有内容基于当前的学术研究和临床...