的确，CAR-T药物的高售价始终成为影响其可及性的关键，印度开发的NexCAR19在载体生产环节实现了生产成本的降低，有利于提高癌症治疗的可及性，并给研发人员提供了一个策略，有望在降低生产成本、保证疗效的前提下，改善更多实体瘤患者的预后。参考资料：[1]Mallapaty S. Cutting-edge CAR-T cancer therapy is now...
Cutting-edge CAR-T cancer therapy is now made in India - at one-tenth the cost. Nature. 2024 Mar;627(8005):709-710. doi:10.1038/d41586-024-00809-y. PMID: 38514877. [2]AACR: Novel allogeneic CAR T cell therapy delivers promising early results in patients with metastatic clear cell ...
1. Cutting-edge CAR-T cancer therapy is now made in India — at one-tenth the cost (nature.com)2. India’s First Homegrown CAR T-Cell Therapy - NCI (cancer.gov)3.Mira's Lymphoma Warrior Journey: Hope and CAR-T Therapy - Mindful Cells 4.Phase I Trial of Humanized CD19 CART-Cell ...
通用型CAR-T(UCAR-T)可实现生产流程的规模化和标准化，可将生产成本降低90%，也期待着CAR-T治疗成本降低来惠及更多患者。资料来源：（1）Chimeric antigen receptor-T cell therapy manufacturing: modelling the effect of offshore production on aggregate cost of goods.（2）Structural evolution and prospect of...
周末愉快呀! 周六的早晨又“早早”的醒了,真实头大。 感觉不会再睡着了,躺着也只是天马行空的瞎想,索性就起床了,干点实实在在的事,那就先把小文章发了吧。 上一期分享下CAR-T cell结构等,本次分享CAR-T 细…
1. Cutting-edge CAR-T cancer therapy is now made in India — at one-tenth the cost (nature.com) 2. India’s First Homegrown CAR T-Cell Therapy - NCI (cancer.gov) 3.Mira's Lymphoma Warrior Journey: Hope and CAR-T Therapy - Mindful Cells ...
CAR-T细胞技术是一种革命性的细胞疗法,2017年诺华公司推出第一代CAR-T疗法,这引领了其他形式的CAR-T药物的发展。 在23日的大会上,Dolcera中国区生物医药首席专家金实为大家带来“CAR-T Cell Therapy专利态势及研发趋势分析”相关观点分享。 知产前沿现将金老师的现场主题发言内容整理成文,供医药知识产权从业人员参考...
[3]. Lin JK, Muffly LS, Spinner MA et al. Cost effectiveness of chimeric antigen receptor T-cell therapy in multiply relapsed or refractory adult large B-cell lymphoma. J. Clin. Oncol. 37(24), 2105–2119 (2019).[4]. Kaiser Health News. Cascade of costs could push CAR-T therapy to...
[3]. Lin JK, Muffly LS, Spinner MA et al. Cost effectiveness of chimeric antigen receptor T-cell therapy in multiply relapsed or refractory adult large B-cell lymphoma. J. Clin. Oncol. 37(24), 2105–2119 (2019). [4]. Kaiser Health News. Cascade of costs could push CAR-T therapy ...
尽管CAR - T 疗法在肠癌治疗中还面临诸多挑战,但随着研究的不断深入和技术的持续创新,其未来发展前景广阔。相信在不久的将来,CAR - T 疗法有望成为肠癌治疗的重要手段,为肠癌患者带来更多的生存希望。 参考文献: 1. June CH, O'Connor RS, Kawalekar OU, Ghas...