Table 2 Comparison of CAR T, NK and macrophages Full size table One major advantage of CAR NK cells over CAR T cells is the source of immune cells. Due to alloreactivity and graft-versus-host disease (GVHD), CAR T therapy requires the use of autologous T cells. As these patients are ...
This study is unusual in directly comparing car drivers’ and motorcyclists’ attitudes, although the motorcyclists in this study were also car drivers. The majority of comparison studies have focussed on comparing the two road users’ behavioural responses in simulation tests (Horswill and Helman, ...
et al. A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy. J. Clin. Invest. 121, 1524–1534 (2011). CAS PubMed PubMed Central Google Scholar Harris, D. T. & Kranz, D. M. Adoptive T cell therapies: a comparison of T...
Comparison of IL-2 vs IL-7/IL-15 for the generation of NY-ESO-1-specific T cells. Cancer Immunol. Immunother. 68, 1195–1209 (2019). CAS PubMed Google Scholar Alizadeh, D. et al. IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell...
For EN590, there was only one biological replicate and thus it was not possible to perform significance analysis (Fig. 8). However, comparison of the mean dot intensity to vehicle indicated similar a trend for increased CXCL8, M-CSF and IL-18 BP and possibly also for vitamin D binding ...
Comparison of Head, Neck, and Chest Injury Risks between Front- and Rear-Seated Hybrid III 50th-Percentile Male ATDs in Matched Frontal NCAP Tests The objective of this study was to compare head, neck, and chest injury risks between front and rear-seated Hybrid III 50th-percentile male anthro...
Bispecific CAR-T cells, also known as dual CAR-T cells, express two distinct CARs simultaneously on the surface of a single cell and demonstrate enhanced antitumor efficacy in comparison to Pooled CAR-T cells. For example, in a glioblastoma model, bispecific CAR-T cells co-expressing IL13Rα...
NK cells products are considered “hard-to-engineer” in comparison with T cells. To ameliorate NK cells transduction efficiency, lentiviral transductions have been significantly improved by incorporating new transduction enhancers which would help viral entry such as polybrene, (a cationic polymer frequen...
(FOXO1-ADA) in mouse HER2-specific CAR T cells or wild-type FOXO1 in human Lewis Y CAR T cells improved metabolic fitness, ultimately leading to enhanced control of solid tumours. Notably, FOXO1 overexpression maintained CAR T cell ‘stemness’ and enhanced persistence to a greater extent than...
Statistical significance between before, during and after the critical curve was found for delta,alpha,beta, point of regard and change in gaze vector. (C) shows the p-values obtained with t-test. Full size image Here we considered a comparison between the neurobehavioral signature of the ...