Using a random effect model the rate difference (RD) in favour of capsaicin cream was RD=0.25 (95% CI=0.15, 0.35). Capsaicin cream was also better than placebo in providing pain relief in osteoarthritis: OR=4.36 (95% CI=2.77, 6.88) and RD=0.29 (95% CI=0.20, 0.37) and in psoriasis...
Capsaicin is widely used in medicine, especially in the form of creams and ointments for topical application to relieve pain from conditions such as arthritis, shingles, and diabetic neuropathy. In the food industry, capsaicin is an essential ingredient in hot sauces and spice blends. It is also...
Significant pain reduction (57% in osteoarthritis patients and 33% in rheumatoid arthritis patients) has been documented using capsaicin cream in the subjects in a study [7]. Capsaicin has been used in the management of neuropathic discomfort, diabetic and HIV-caused neuropathy, post-herpetic ...
4.6. Preparation of the NP Cream for Topical Application A 1 mg aliquot of NPs was suspended in 20 μL of sterile water by vortexing for 1 min, and then placed in an ultrasonic bath for 5 min. The resultant NP suspension was stirred into 80 mg of Vanicream. Then resultant preparation ...
[10,11]. Furthermore, capsaicin has shown potential as an anti-inflammatory agent, with applications in the treatment of conditions such as arthritis and psoriasis in humans [12]. Notably, the combination of capsaicin and silibinin has been reported to effectively suppress lipopolysaccharide (LPS)-...
In a double-blind, randomized 4-week trial, 70 patients with OA and 31 patients with RA applied either capsaicin 0.025% cream or placebo to painful knees [110]. Most patients continued concurrent arthritis medications. After 4 weeks of capsaicin treatment, RA pain was reduced by 57% and OA...