体外获能成熟(CAPA-IVM)是一种不经过或经过极少量卵巢刺激后恢复的卵母细胞体外成熟的新方法,该方法在卵母细胞体外成熟过程中纳入了获能步骤,可增强卵母细胞的生长能力。CAPA-IVM是一种患者友好型辅助生殖技术方法,可能成为常规卵巢刺激和IVF的替代方案,从而减轻患者的治疗负担。
Capacitation-IVM (CAPA-IVM)Pre-maturation (pre-IVM)c-type natriuretic peptide (CNP)Cumulus-oocyte gap junction communicationOocyte qualityPurpose Oocyte in vitro maturation (IVM) is a patient-friendly reproductive technology but lower success rates than IVF have limited its uptake. Capacitation-IVM ...
CAPA-IVM yielded significantly (p < 0.0001) less GV-arrested oocytes and larger oocyte diameters (p < 0.05) than STD IVM. Conclusions CAPA-IVM brings significant improvements in maturation and embryological outcomes, most notably to oocytes from small antral follicles (< 6 mm), which can be ...
IVM, embryo culture, cryopreservation, endocrinology, maternal physiology, fertility, andrology, reproductive immunology, reproductive biology, lactation, pregnancy, contraception, stem cell biology, genetics, cell biology, animal production, theriogenology, CSIRO , csiro publishing , publications , science ,...
CAPA-IVM yielded significantly (p < 0.0001) less GV-arrested oocytes and larger oocyte diameters (p < 0.05) than STD IVM. Conclusions CAPA-IVM brings significant improvements in maturation and embryological outcomes, most notably to oocytes from small antral follicles (< 6 mm), which can be ...
Purpose To investigate the effectiveness of a biphasic IVM culture strategy at improving IVM outcomes in oocytes from small follicles (< 6 mm) compared with routine Standard IVM in patients with polycystic ovaries.Sanchez, FlorLe, Anh H.Ho, Vu N. A.Romero, SergioVan Ranst, HeidiDe Vos, ...
significantly lower multiple pregnancy rate as compared to day-3 embryo transfer group (4.6% vs. 18.0%; p=0.005, respectively).#Conclusions: Blastocyst transfer had comparable live birth rate but lower multiple pregnancy rate to day-3 embryo transfer after the first FET following CAPA-IVM in ...
Capacitation in vitro maturation (CAPA-IVM) represents the latest refinement of IVM protocols and provides in vitro matured oocytes with improved competence. This case report describes the first successful live birth following oocyte vitrification from a CAPA-IVM cycle. This milestone achievement holds ...
Furthermore, oocyte in vitro maturation (IVM) is another important step that could be related to polyspermic fertilization and low embryo production. The presence of nitric oxide syn-thase (NOS), the enzyme that produces nitric oxide (NO), has been detected in the oviduct, the ovary, the ...
After 27 h of in vitro maturation (IVM), oocytes were denuded, washed and randomly divided into 4 groups. Group 1 consisted of in vitro matured oocytes ( n = 627) co-incubated with sperm in a 50 μl drop of TALP medium containing a 6 mg/ml crystalline bovine serum albumin (BSA) ...