Dipartimento di Matematica, Università degli Studi di Perugia, Via Vanvitelli 1, 06100, Perugia, Italy Giorgio Faina & Fernanda Pambianco Rights and permissions Reprints and permissions About this article Cite this article Faina, G., Pambianco, F. On the spectrum of the valueskfor which a comple...
PCSK9 was recently implicated in MHC-I degradation via the interaction of an R-X-E motif with M2. Our molecular modeling suggests that Arg68-X-Glu70 of the MHC-I family member HLA-C [26] may interact with M2 Glu567 and Arg549, respectively (Figure 7A). Remarkably, mutation to Ala ...