(This device is a business card scanner.) However, the drivers for the TS8320 are not in the 64-bit directory, only in the 32-bit directory C:\Windows\twain_32\SG20\TS8300 series. So that seems to be the problem. Is a 64-bit version of the Canon scanner drivers available?...
The scanner wouldn’t work with my iMac either, after the last iOS upgrade to Monterey 12.1.2. Had to go to Hamrick and pay $20 to download a driver. Better than buying a new printer, especially since I have almost 3 full boxes of toner cartridges. Best of luck...