it is the only hair test with safeguards validated by the FBI to protect those tested from false positive results by differentiating between ingestion versus external exposure to a drug. Our clients confidently make policy decisions knowing that we go the extra mile to ensure fairness to those tes...
In the light of the serious consequences of positive test results the mechanisms of drug incorporation into hair urgently need scientific evaluation. Here we show that neither THC nor THCA-A are incorporated into human hair in relevant amounts after systemic uptake. THC-COOH, which is considered ...
In the light of the serious consequences of positive test results the mechanisms of drug incorporation into hair urgently need scientific evaluation. Here we show that neither THC nor THCA-A are incorporated into human hair in relevant amounts after systemic uptake. THC-COOH, which is considered ...
A positive cannabinoids workplace drug test following the ingestion of commercially available hemp seed oil. Urine specimens collected from the volunteer were subjected to standard workplace urine drug testing procedures, and the following concentrations of 11-nor-... RE Struempler,N Gordon,FM Urry...
Sex differences in response to the acute effects associated with abuse liability of cannabis and cannabinoids have been examined using double-blind, placebo-controlled laboratory procedures. End points that have been assessed include subjective drug ratings related to positive drug effects and cue-induced...
In contrast to these positive effects, however, another early study on this topic reported that THC increases breast cancer growth and promotes tumour cell spread by inhibiting the antitumour immune response via enhancement of Th2-associated cytokines [138]. However, the study design used here was...
Other possible mechanisms include modulation of serotonergic transmission (particularly positive allosteric modulation of 5-HT1A) (Jesus et al., 2019), desensitisation of TRPV1 (Anand, Jones, Korchev, Pacchetti, & Sodergren, 2020) and antagonism of GPR55 (Ryberg, Sjögren, Hermansson, & Ele...
Co-treatment of CBD with clobazam was a significant predictor of a positive treatment response of greater than 50% responder rate. There was an odds ratio (OR) of 3.3 for total seizure reduction and of 1.9 for convulsive seizures. The OR evaluates whether the odds of a certain event or out...
(or no significant) effect of cannabis usage. However, it is essential to consider the limitations of subjective self-reporting, potentially biased sampling of patient advocacy groups (over-reporting positive effects), and uncontrolled differences in CBD:Δ9-THC content in various strains of cannabis...
End points that have been assessed include subjective drug ratings related to positive drug effects and cue-induced craving. Similar to studies investigating sex differences in the therapeutic effects of cannabinoids, sex differences related to abuse liability were mostly analyzed as an exploratory aim ...