Canine Parvovirus Monoclonal Antibody offers targeted treatment of canine parvovirus (CPV) to help reduce burden of care for this deadly disease.
“Parvo doesn’t have to be a death sentence. Our innovative treatment for parvovirus can help veterinarians and pet owners alleviate the emotional toll associated with parvo,” said Dr. Jennifer Miller, technical veterinarian with Elanco. “Elanco’s Canine Parvovirus Monoclonal Antibod...
Commercially available test systems include the following: SNAP Parvovirus (IDEXX), VetScan® Canine Parvovirus (Abaxis), Witness® Parvo (Synbiotics), SAS™ Parvo (SA Scientific), Fastest® Parvo Strip (MegaCor), and the Speed® Parvo (Bio Veto Test). These are all monoclonal antibody...
IgG antibody titers above dilutions of 1:810 are considered protected. Intended use The principle of the CPV testkit is based on the detection of antibodies against Parvo virus. The Parvo virus is attached to the solid phase by use of a monoclonal antibody. After the attachment of the antige...
CPV VP2 gene was introduced into polyhedrin-based BmNPV transfer vector pBmKSK3, and recombinant virus BmK1-Parvo was prepared. When anti-CPV.VP2 monoclonal antibody was employed in immunofluorescence staining, an intense signal was observed within BmK1-Parvo-infected Bm5 cells ...
, 1997). Although antigenic differences between virus strains were found by monoclonal antibody, the vaccines cross-protect against different strains (Wiktor and Koprowski, 1980). Most of the inactivated rabies virus vaccines on the market today induce immunity in dogs that lasts for 3 years. ...
Parvoviral enteritis in dogs is caused by canine parvovirus strain 2 (CPV–2) of the family Parvoviridae, genus Protoparvovirus, species Carnivore protoparvovirus 1. Currently, there are three antigenic variants, 2a, 2b, and 2c. Parvoviruses are nonenveloped, single-stranded DNA viruses. Clinica...
Comparison of isolates of canine parvovirus by monoclonal antibody and restriction-enzyme analysis Vet. Rec., 138 (1996), pp. 495-496 CrossrefView in ScopusGoogle Scholar Johnson and Spreadbrow, 1979 R.H. Johnson, P.B. Spreadbrow Isolation from dogs with severe enteritis of a parvovirus relat...
(Battilani et al., in press), is characterized by the presence of glutamic acid in residue 426 of the VP2 protein, the epitope which distinguishes the 2a/2b variants, and this amino acid change causes an antigenic difference detectable using monoclonal antibodies (Nakamura et al., 2004) so...
The presence of a single aa change among CPV-2a, -2b and -2c confers different antigenic properties, as evidenced by the different reactivity to specific monoclonal antibodies (Nakamura et al., 2004). However, the variants lack clear monophyletic segregation due to the accumulation of other ...