Mast cell tumorGradingc-KitCanine cutaneous mast cell tumors (MCTs) are among the most common canine cutaneous tumors, with highly variable biological behavior. This review describes in detail current approaches for cytologic and histologic diagnosis and prognosis, including advantages and limitations of...
think about [mast cell tumors] I just want pet owners and veterinarians to remember the majority of them are treatable and even for those subset of high grade mast cell tumors, a lot of the recent studies show if we treat them aggressively they can actually have a really good prognosis. ...
Differences in the frequency of somatic mutations imply their direct association with the neoplastic transformation. However, their functional consequences and clinical significance are not clear. The mutations may be used for diagnosis and prognosis of canine mast cell tumours in the future. Findings M...
Mast cells (MCs) are well known for their neoplastic transformation in solitary and multiple cutaneous mast cell tumours (MCTs), as well as visceral and sy... MM Welle,CR Bley,J Howard,... - 《Veterinary Dermatology》 被引量: 237发表: 2008年 Prognosis of Canine Mast Cell Tumors: A Comp...
Establishment and characterization of a new canine mast cell tumor cell line. J Vet Med Sci. 2001;63(9):1031–4. Article CAS PubMed Google Scholar Takahashi T, Kitani S, Nagase M, Mochizuki M, Nishimura R, Morita Y, et al. IgG-mediated Histamine release from canine mastocytoma-derived...
Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision Clin Cancer Res, 15 (11) (2009), pp. 385...
CSF-1 and CCL2 are known mod- ulators of the fate of macrophages, both driving the production of M2 cells and being correlated to poor prognosis in cancer [5, 28]. Our understanding of the interaction between TAMs and cancer cells is still evolving [6], as is the very classifica- ...
Furthermore, the samples used for the tumor lysates were not microdissected and thus contain tumor, stroma and non-neoplastic cell infiltrates. When comparing receptor mRNA and protein levels in a tumor to “histologically normal lung” tissue within the same individual, it is possible that ...
L. 1996 Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Research, 56 20 (October 15 1996), 4625 4629 , 0008-5472 41. Mantovani A. Sozzani S. Locati M. Allavena ...
(malignant tumor with a better prognosis as compared to other malignant lesions) and 'tubular carcinomas' (showing well differentiated morphology and no evidence of infiltration); Class 3: 'simple carcinomas' and 'complex carcinomas' (representing aggressive forms of malignant tumors). Classes 0, ...