PROMPT 7.5: Could you summarize the key conclusions you have drawn from the conversation so far? Results Exploring the potential utility of LLMs for knowledge-driven candidate biomarker prioritization We hypothesized that LLMs could mitigate challenges in knowledge-driven curation and prioritization of ...
Genome for REPositioning drugs (GREP) software. A pathway-set enrichment analysis was also performed using Gene2Drug to identify drug repositioning candidates. Using RHR significant GO biological processes as input, pathway expression profiles are created and ranked according to the p-value of their K...
Identification of key candidate genes in runs of homozygosity of the genome of two chicken breeds, associated with cold adaptation. Biology (Basel). 2022;11:547. CAS PubMed Google Scholar Zhang M, Han W, Tang H, Li G, Zhang M, Xu R, Liu Y, Yang T, Li W, Zou J, et al. ...
In general, genes involved in this cellular process were up-regulated under abiotic stress as a protective mechanism against key enzymes activity (see Additional file 1). Regulation of the translational machinery is considered an integral component in the cellular stress response [77, 93]. It has...
Gene expression profiling using high-throughput screening (HTS) technologies allows clinical researchers to find prognosis gene signatures that could better discriminate between different phenotypes and serve as potential biological markers in disease di
The key advantage of sequencing an entire genome is that every trait under study will benefit from the genomic and genetic resources already generated (for example, reference genome sequence, resequenced genotypes, and mapping populations), and no significant additional investment will need to be made...
20 Svetkey LP, Harris EL, Martin E, Vollmer WM, Meltesen GT, Ricchiuti V, Williams G, Appel LJ, Bray GA, Moore TJ, Winn MP, Conlin PR. Modulation of the BP response to diet by genes in the renin-angiotensin system and the adrenergic nervous system. Am J Hypertens 2011; 24: 209...
Chao D-Y, Baraniecka P, Danku J, Koprivova A, Lahner B, Luo H, Yakubova E, Dilkes B, Kopriva S, Salt DE. Variation in sulfur and selenium accumulation is controlled by naturally occurring isoforms of the key sulfur assimilation enzyme ADENOSINE 5′-PHOSPHOSULFATE REDUCTASE2 across the ...
and protein modelling. Two key gene families involved in both the synthesis and degradation of alginate were suggested to have been acquired by the common ancestor of brown algae and their closest sister speciesSchizocladia ischiensis.Our analysis indicates that this assumption can be extended to ad...
2020RW002]; the National Key Research and Development Program of China [No. 2017YFD0500103]; the National Natural Science Foundation of China [No. 31772747]; the Jilin Province Science and Technology Development Projects [No. 20200402043NC]; and the Science and Technology Research Program during ...