L. Enhancements to the ADMIXTURE algorithm for individual ancestry estimation. BMC Bioinformatics 2011; 12(1). Francis RM. Pophelper: an R package and web app to analyse and visualize population structure. Mol Ecol Resour. 2017;17(1). Zhang C, Dong SS, Xu JY, He WM, Yang TL. PopLD...
The least absolute shrinkage and selection operator logistic regression model and support vector machine-recursive feature elimination algorithm were combined to screen potential biomarkers. The test datasets validated the expression levels of these biomarkers, and the area under the curve (AUC) was ...
variable errors, insensitivity to monotonic transformation of variables, and high predictive power. In this study, we implemented the PURF algorithm by extending the ensemble and tree modules in the Python scikit-learn package105and developed a lightweight Python package. The framework proposed by Li ...
It might be because the injection of spores elicited a stronger non-specific immune reaction than oral immunization, such as lysozyme and complement system, which might also take part in the elimination of C. sinensis in mice [23]. However, the mechanism involved deserves further exploration. ...
The development of a vaccine would help achieve the WHO 2030 Roadmap for NTD target of elimination of ascariasis as a public health p roblem2. Over the last few decades there have been a number of studies aiming to develop vaccines against Ascaris12–18. The vaccines in these trials ...
It might be because the injection of spores elicited a stronger non-specific immune reaction than oral immunization, such as lysozyme and complement system, which might also take part in the elimination of C. sinensis in mice [23]. However, the mechanism involved deserves further exploration. ...
According to the World Health Organization reports, billions of people around the world are at risk for malaria disease and it is important to consider the preventive strategies for protecting the people that are living in high risk areas. One of the mai
A multi-epitope prophylactic/therapeutic vaccine targeting the pathogen's major structural and functional infective proteins (E, NS3, and NS5 proteins in this study) would be invaluable to achieve the current elimination goal. The present study was conducted with the directive to design a chimeric ...
vaccine construction. VaxiJen 2.0 server is based on auto and cross-covariance (ACC) transformation of protein sequences into uniform vectors of major amino acid properties was used to evaluate the antigenicity of the vaccine. The VaxiJen algorithm is mainly based on the method of sequence ...
Genes from each of the five correlation networks for the regulated genes were taken as input to the NetNC algorithm if they were found in no more than two IMMUNETS networks; in order to produce five focus networks. NetNC analysis used the ‘FTI’ setting and HumanNet as the base network ...