and other scholars to my own case. Dairy foods weren’t the only culprits – I had to make a serious lifestyle change and alter my diet considerably. But I felt a whole lot better and there were some side benefits, too, such as a noticeable improvement in the appearance of my skin....
Taken together, these results indicate that the disease-promoting functions of TYK2 depend on the presence of T cells and/or B cells and that these cells contribute to the control of C. albicans growth in the skin but facilitate fungal dissemination to kidneys. Moreover, the data suggest that...
pictures of the infected skin on day 2 p.i. A GMS staining of the skin sections is shown. PBS: Data are representative for sections from 8 (WT) and 11 (Tyk2-/-) mice. Anti-Ly6G: Data are representative for sections from 9 (WT) and 6 (Tyk2-/-) mice. Scale bar: 50 μm.fF...
VMA11, antifungal resistance C andida albicans is a common human commensal of the skin and gastrointestinal and genitourinary tracts; it is also the most prevalent human fungal pathogen, causing a range of infections from superficial infections of the skin to life-threatening systemic infections (1...
Is Biofase safe for someone who has had "intestinal erosions" (as in Crohn's disease) ? Biofase die off reactions Why are the enzymes in biofase measured in MG and not in FCC (Food Chemical Codex)? Shouldn't the enzyme activity of products be measured and reported in FCC units? Thes...
The diagnosis of calciphylaxis is mainly clinical and skin biopsy is infrequently done because of the risk of poor healing and secondary infections. Despite aggressive treatment regimens, mortality is high. Here, we report the case of a 44-year-old female end-stage renal disease patient with ...
Disease pathogenesis is enhanced by the organism’s propensity to colonize skin, adhere to medical devices, form biofilm, and secrete hydrolytic enzymes [1], [2]. Further, we have recently shown that lipid metabolism is an important pathway for C. parapsilosis virulence by demonstrating significant...
We previously reported that intra-amnioticC. albicansrapidly colonizes the amniotic fluid, causing inflammation of the fetal skin and lungs, and progresses into a fetal systemic inflammatory response causing fetal death within 5 days after exposure [16,17]. In the present study, we show that fluco...
Vaccines targeting invasive pathogens constitute a significant advancement in disease prevention, and the development of a successful anti-Candida vaccine emerges as a clear strategy for candidemia prevention. Candida infections, particularly those caused by drug-resistant strains like Candida auris, are on...
Background: Infections caused by Candida spp. have become one of the major causes of morbidity and mortality in immunocompromised patients. Therefore, new effective fungicides are urgently needed, especially due to an escalating resistance crisis. Method