a: Every breath has come to love you : 每呼吸来爱您[translate] aAdvanced breast cancers frequently metastasize to bone, resulting in osteolytic lesions, yet the underlying mechanisms are poorly understood. Here we report that nuclear factor–κB (NF-κB) plays a crucial role in the osteolytic...
Cancers that metastasize to lymph nodes while very small have properties in common with these interval surfacing and, presumably, faster growing cancers. Cancer 53:96-98, 1984.doi:10.1002/1097-0142(19840101)53:13.0.CO;2-AJohn Wiley & Sons, LtdCancer...
a.Any of various malignant neoplasms characterized by the proliferation of anaplastic cells that tend to invade surrounding tissue and metastasize to new body sites. b.The pathological condition characterized by such growths. 2.A pernicious, spreading evil:A cancer of bigotry spread through the commu...
2. Malignant myoepithelioma of breast 2.1. Case report A 58 year old lady who was known to have a ductal adenoma of her left breast for 3 years was identified on screening mammogram which suggested that the adenoma had enlarged in size and looked atypical in appearance and was graded as in...
Solid cancers metastasize to bone by a multistep process that involves interactions between tumor cells and normal host cells. Some tumors, most notably br... Gregory,R.,Mundy,... - 《Cancer》 被引量: 847发表: 1997年 Latent bone metastasis in breast cancer tied to Src-dependent survival si...
Occasionally, however, a single cell acquires a set of sufficiently advantageous mutations that allows it to proliferate autonomously, invade tissues and metastasize. The catalogue of somatic mutations in a cancer genome Like all the cells that constitute the human body, a cancer cell is a direct ...
The first patient has been dosed with QBS72S in a phase 2 trial (NCT05305365) evaluating the agent for the treatment of brain metastases of breast cancers.1 "Breast cancer is one of the most common tumors to metastasize to the brain. Breast cancer brain metastases worsen prognosis, ne...
(kidney) and colorectal. They discovered thatlung cancerand melanoma showed a higher likelihood for the metastasis to be at the frontal and temporal lobes (which sit behind the ears). Breast, renal and colon cancers had a higher propensity to spread to the back of the brain, such as the ...
to other subtypes, we further subcategorized OBC patients into two subgroups, an intermediate breast cancer (IBC) for those between 40 and 60 and an elderly breast cancer (EBC) group for those over 60 (Additional file 1: Fig. S2A–B). As a result, we discovered that EBC patients ...
Metastasis Metastasize to Site of Origin Status of Form Tumor Neck Lymph Node P53 Status and Cell Line in Patient Patient in Xenograft in Xenograft Mutation JHU-019 Tongue Positive lymph yes yes mutated node frameshift and early termination at 169 caused by deletion at 138 PCI-15A* Oral cavit...