Conclusion: Men with advanced prostate cancer may live for several years after diagnosis of bone metastases; however, pain and other difficult symptoms are problematic. Pain is effectively treated with palliative radiotherapy, but careful assessment and intervention of other difficult symptoms must be ...
Progenitor marker CD133 mRNA is elevated in peripheral blood of cancer patients with bone metastases. PURPOSE: We examined whether RNA expression of CD133, a surface molecule expressed on progenitors from hematopoietic and endothelial lineages, and CD146, a... N Mehra,M Penning,J Maas,... - ...
The Breast Cancer to Bone (B2B) Metastases Research Program consists of a prospective cohort of incident breast cancer patients and four sub-projects that are investigating priority areas in breast cancer bone metastases. These include the impact of lifestyle factors and inflammation on risk of bone...
Considering the specificity, sensitivity, cost-effectiveness, and accessibility of various diagnostic methods, imaging evaluation for bone metastasis screening is recommended for patients with stage 3 or higher breast cancer (except for T3N1M0 patients) and those experiencing bone pain, pathological fractu...
Upon arrival, cancer cells establish interactions with various bone-resident cells during the process of colonization. These interactions, to a large degree, dictate cancer cell fates at multiple steps of the metastatic cascade, from single cells to overt metastases. The bone microenvironment may even...
She was found to have stage 4 breast cancer with multiple bone metastases 4 years prior. Since then, she has been treated with an aromatase inhibitor and denosumab. The patient had no obvious history of trauma. One day, while walking, pain appeared in her left shin. A few days after the...
MORE THAN 90% OF MEN WITH ADVANCED PROSTATE CANCER WILL DEVELOP BONE METASTASES2 Most men with advanced prostate cancer will experience a dangerous transformation in their disease when primary tumor cells invade the bone.1-3 SEER=Surveillance, Epidemiology, and End Results. THE BONE SUPPORTS A ...
Additionally, bone metastases are more frequent in follicular and medullary thyroid cancers, requiring closer bone surveillance in patients with these histologies. Emerging data also suggest that treatments such as multikinase inhibitors (MKIs) can be less effective in controlling bone, as opposed to ...
We therefore organized a Japanese expert panel meeting for the management of prostate cancer with bone metastases, a forum at which experts could share their experiences and reach consensus on the key clinical questions related to the management of prostate cancer with bone metastases. The main focus...
Identification of the optimal candidates to benefit from surgery and chemotherapy among elderly female breast cancer patients with bone metastases Yuchen Hu ,Junfeng Tang &Qing Gao Article 08 February 2025|Open Access Association between magnesium depletion score and prostate cancer ...