Plant-based oils vs. butter What makes plant-based oils healthier than butter is their high unsaturated fat content, which can help lower bad cholesterol and boost good cholesterol, which helps to reduce your risk of heart disease and stroke. These healthy fats have also been shown to have an...
noting that cardiotoxicities linked to cancer treatments include cardiomyopathy (heart disease), atrial fibrillation (irregular heartbeat), arterial high blood pressure and myocarditis (heart inflammation).
Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell. 2017;171:273–85. Article CAS Google Scholar Dai C, Chen X, Li J, Comish P, Kang R, Tang D. Transcription factors in ferroptotic cell death. Cancer Gene Ther. 2020. https://doi.org/...
based on chronic CoQ10 supplementations) would act to increase the fluidity of the plasma membrane of tumor cells/CTCs and counteract ECM-mediated oncogenic signaling, representing an interesting therapeutic level of action in BC patients with aggressive disease course. ...
[112]. Another study suggested an association between PDPN+CAFs and prolonged disease-free survival (DFS) in CRC patients [113]. PDPN could also act as a co-inhibitory receptor on T cells, and T cell specific PDPN conditional knockout mice exhibited delayed tumour growth [114]. Macrophage-...
We considered exploring clinical heterogeneity by the indication of spironolactone (any, hypertension, or heart failure) and by gender (female vs male), and methodological heterogeneity by the risk of confounding and immortal time bias (low vs high). Sensitivity analyses were performed to evaluate ...
Mesenchymal stromal cells (MSCs) are important cellular constituents of tumor stroma that play an active role in tumor development. Complex interactions between MSCs and cancer promote tumor progression by creating a favorable milieu for tumor cell proli
we will conquer this disease. With my aunt, uncle, and father recently diagnosed with cancer, I realized the time to join the fight is NOW. This isn’t a distant problem; it’s a call to action for a cancer-free future for my family and yours. Stand in my corner, or join me in...
WO2007046489A1 2007-04-26 THERAPEUTIC AGENT FOR HEART DISEASE WO2007058194A1 2007-05-24 INHIBITOR OF CYTOTOXIC T CELL INDUCTION WO2007061029A1 2007-05-31 THERAPEUTIC AGENT FOR PROSTATE CANCER WO2007067976A2 2007-06-14 METHOD OF USING IL6 ANTAGONISTS WITH PROTEASOME INHIBITORS WO2007076927A1 2007-07...
ORR was higher with margetuximab: 25.2% vs 13.7%. In a planned exploratory analysis by FcRIII genotype, treatment benefit was enriched in the population with FcγIIIa 158F allele. In this subgroup, a reduction of 32% was evidenced in disease progression. In addition, in this population, ...