Cancer treatment vaccines boost the immune system's ability to find and destroy antigens. Often, cancer cells have certain molecules called cancer-specific antigens on their surface that healthy cells do not have. When a vaccine gives these molecules to a person, the molecules act as antigens....
Peregrine Pharmaceuticals Recombio Roche Roche Seattle Genetics Valeant Pharmaceuticals Related Topics Cancer Vaccines Clinical Trials Related Products Global Cancer Vaccines Market by Technology (Antigen, Dendritic Cells, Recombinant Cancer Vaccines), Treatment Method (Preventive Vaccine, Therapeutic Vaccine), Ap...
The vaccine, which has not yet been named, targets triple-negative breast cancer, the most aggressive and deadliest form of breast cancer. The vaccine's first clinical trial, the results of which were published last week, found that the vaccine caused no significant side effects and achieved a...
Several published studies have suggested that melanoma vaccine may be effective in the treatment of malignant melanoma and/or prevention of metastasis of melanoma; however, these studies are not adequate to establish the safety and/or efficacy of this therapy. In addition, there have been a number...
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A. et al. Clinical trial results of the HER-2/neu (E75) vaccine to prevent breast cancer recurrence in high-risk patients: from US Military Cancer Institute Clinical Trials Group Study I-01 and I-02. Cancer 118, 2594–2602 (2012). Article CAS PubMed Google Scholar US National Library...
D. Vaccine strategies for the treatment of lymphoma: preclinical progress and clinical trial update. Immunotherapy 8, 1335–1346 (2016). Article CAS PubMed Google Scholar KA, F. Treatment of B-cell lymphoma with monoclonal anti-idiotype antibody. N. Engl. J. Med. 307, 686–687 (1982). ...
Professor Peter Johnson, national clinical director for cancer at the NHS, said the vaccine may allow clinicians to prevent cancer tumours returning after surgery. Trials have enrolled dozens of people, NHS England said, with the majority expected to take part from 2026 onwards. ...
advanced melanoma.124The SLP vaccine can induce a robust T cell response with immunomodulatory adjuvants, including polyriboinosinic-polyribocytidylic acid-poly-L-lysine carboxymethylcellulose (poly-ICLC), cytosine-phosphate-guanine (CPG) and Toll like receptor (TLR). In a phase 1 clinical trial ...
2022年美国临床肿瘤学会(American Society of Clinical Oncology, ASCO)报道了一种基于血液cfDNA甲基化的早诊方法HepaAiQ,灵敏度达87.2%,对早期肝癌也显示出优异的诊断性能(灵敏度为83.2%)[10]。中国学者通过检测cfDNA的5-羟甲基胞嘧啶、核小体足迹、5‘末端基序和碎片概况从3 234人队列中构建并验证了HCC检测模型...