However, we find that tumor gene expression is a more powerful predictor of prognosis, across a wider range of cancer types, than microbial abundances. Moreover, we find five cancer-drug pairs where tumor microbial abundances are more predictive of patient drug response than clinical covariates ...
癌症类型 题目 URL BLCA Tumor-infiltrating M2 macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6610042/ BRCA Relevance of Tumor-Infiltrating Immune Cell Composition and Functionality for Disease Outcome in Brea...
immune cell infiltrate, levels of genetic aberrations, and patient prognosis (Thorsson et al., 2018). In terms of overallimmune cell infiltration, cancer types dominated by wound healing, IFNγ-dominant, and inflammatory immune subtypes, including lung cancer,pancreatic cancer, andmelanoma, show the...
Accurately determining the molecular subtypes of breast cancer is important for the prognosis of breast cancer patients and can guide treatment selection. In this study, we develop a deep learning-based model for predicting the molecular subtypes of breast cancer directly from the diagnostic mammography...
"What is especially remarkable is their newly discovered capacity to act as antigen-presenting cells, maturing and rallying T cells against cancer. In addition, the abundance of antigen-presenting neutrophils is associated with improved patient prognosis across many tumor types revealed in this study,...
Hypoxia in the tumor microenvironment is common in advanced cancer and is related to poor prognosis and a worse survival rate. A growing body of evidence has discovered that hypoxia can promote cancer cell invasion, metastasis, and EMT. All these events can promote stemlike characteristics in canc...
Pancreatic cancer is a difficult disease. Even for surgically resectable (and therefore potentially curable) pancreatic tumors, the risk of cancer recurrence and subsequent death remains high. Consequently, the prognosis of pancreatic cancer usually ranges from fair to poor. ...
Atypical fibroxanthomausually appears on the head or neck in people whose skin was severely exposed to the sun. Rapidly growing, dome shaped, red nodules may become ulcerated. Treatment is by complete surgical removal, prognosis is good.Picture of atypical fibroxanthoma. ...
Fig. 2. Genes commonly down-regulated in DESNT poor prognosis prostate cancer. (A) Number of genes with significantly altered expression in DESNT cancers compared to non-DESNT cancers (p < 0.01 after correction for false discovery rate). Forty-five genes had lower expression in DESNT cancers...
But those numbers are averages. They don’t necessarily predict what will happen to you. Your prognosis, or chances of recovery, will depend on the specific traits of your cancer, how early or late it was caught, your overall health, and other things. ...