This breakthrough is the first to target G12D and gives us a firm foothold to fight this devastating mutation.”In 20132, Dr Shokat and his team developed the first cancer drugs to stop a different K-Ras mutation, G12C. Since then, two therapies have been approved for use in lung and...
On Thursday, the French and Canadian scientist was announced as a winner of the prestigious Breakthrough Prize for his pioneering work in CAR T-cell therapy, a new form of treatment that has shown exceptional efficacy against blood cancers. "Over the years, I can't tell you how many times ...
BREAST cancer patients may be a step closer to receiving a more personalised approach to their treatment following research by Cardiff University.A new study by researchers at the University treads new ground in exploring what drives breast cancers to look and behave so differently from one another...
94 By 2023, the US FDA has approved 79 therapeutic monoclonal antibodies, of which at least 48 are used for cancer treatment, as summarized in Supplementary Table 1.95 These monoclonal antibodies are a class of proteins that target specific antigens to exert single or multiple effects for elimi...
ArticleOpen Access6 Jun 2023 Nature Communications ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma Chimeric antigen receptor T (CAR-T) cells represent a breakthrough in the treatment of haematopoietic malignancies, however, in solid tumours this form of immune therapy is...
In addition to a breakthrough therapy designation for a lung cancer drug, this week we’ll be talking a lot about additional side effects and health conditions that may come with a cancer diagnosis, and how to manage them. January 23rd 2025 ...
Researchers atOxford Universityand theUniversity of Birminghamhave made a major breakthrough in cancer treatment by creating the first human bone marrow “organoids” that accurately replicate the key features of human bone marrow. The technology, which is the subject of a patent application filed ...
CANBERRA, May 9 (Xinhua) -- South Australian researchers have made a breakthrough in overcoming drug resistance in patients with rare blood cancer. In a study published on Monday, the team from the University of South Australia (UniSA) and SA Pathology's Center for Cancer Biology said they ...
Molecular understanding and clinical aspects of immunotherapy in the treatment of cancer Advances in Nanomedicine for Cancer Therapy Molecular Cancer invites submissions to this article collection. This Collection aims to explore innovative research and breakthrough developments in the application of nanotec...
New research has identified a potential treatment that could improve the human immune system’s ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells that regulate the immune system, which in turn ...