While cancer-specific survival rate was in favor of patients who undergo early RC for high-risk NMIBC, significant proportion of patients still would be overtreated. In addition, the potential morbidity and mortality of the RC must be taken into consideration. Therefore the careful follow-u...
Metastatic prostate cancer survival rate.Fewer people (about 7%) have more advanced prostate cancer at the time of diagnosis. Once prostate cancer has spread beyond the prostate and nearby structures, survival rates fall. "Distant" prostate cancer has moved into farther-away areas of the body, su...
What is the best time of the month to treat breast cancer? Could breast cancer survival rates be improved simply by timing treatment to a specific stage of the menstrual cycle? Mouse and human data suggest sensitivity to chemotherapy is affected by fluctuations in ovarian hormones. ...
Relative breast cancer survival rate by stage The survival rates by stage are based on the stage at the time of diagnosis. You’ve probably been given a number and letter for your cancer stage. Here, the terms localized, regional, and distant are used instead of numbers and letters. ...
trial evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from ...
Esophageal cancer is often asymptomatic, but experienced clinicians can detect tumors and precancerous lesions with endoscopies. The five-year survival rate is over 90 percent when the tumor is treated during the early stages while the clinical outcomes decline sharply once patients start experiencing...
Table 1. Overall survival (OS) rates in the intent-to-treat population OS rate, %(95% CI) [patients at risk, n]Alectinib (N = 152)Crizotinib (N = 151)Difference, % (95% CI) Year 1 84.3 (78.4–90.2) [120] 82.5 (76.2–88.9) [104] −1.8 (−10.4–6.9) Year 2 72.5 (65.1...
Gastric and pancreatic cancers are the GI cancers with the lowest survival rate, about 5–20%, absence of routinely diagnostic screening protocols and limited availability of therapeutic options [5]. Among the clinical conditions determining metabolic syndrome, hyperglycemia and obesity represent two ...
Early intervention with daratumumab improves survival for patients with high-risk smouldering myeloma Recent results from the phase III AQUILA trial demonstrate the benefit of fixed-duration monotherapy with daratumumab over observation in patients with high-risk smouldering multiple myeloma, which changes th...
Yang et al. show that transcription–replication collisions lead to large tandem duplications, which are frequent in female-enriched, upper gastrointestinal tract and prostate cancers and are associated with poor survival and mutations in specific genes, such asCDK12. ...