Cancer stem cell – Hypoxia – Microenvironment – Angiogenesis – Antitumor therapy – MetastasisModern tumor therapy has achieved considerable progress, but many tumors remain refractory to treatment or relapse following initial remission. Recent evidence points to one possible ...
Cancer stem cells (CSCs) are a subpopulation of tumour cells that possess the stem cell properties of self-renewal and differentiation. Stem cells might be the target cells responsible for malignant transformation, and tumour formation may be a disorder of stem cell self-renewal pathway. Epigenetic...
Modern tumor therapy has achieved considerable progress, but many tumors remain refractory to treatment or relapse following initial remission. Recent evid
Cancer Stem Cell for Tumor Therapy 来自 NCBI 喜欢 0 阅读量: 51 作者: Y Li 摘要: Tumors pose a significant threat to human health. Although many methods, such as operations, chemotherapy and radiotherapy, have been proposed to eliminate tumor cells, the results are unsatisfactory. Targeting ...
Tumor Biol, 31 (2010), pp. 243-253 Google Scholar 4 S. Sell Stem cell origin of cancer and differentiation therapy Crit Rev Oncol Hematol, 51 (2004), pp. 1-28 Google Scholar 5 M.S. Wicha, S. Liu, G. Dontu Cancer stem cells: an old idea—a paradigm shift Cancer Res, 66 (20...
However, selection of cells with a CD133/伪2尾1 integrin/ CD44phenotype enriches for a tumor-initiating population from human prostate cancers. Among the most pressing needs is for enduring therapy in patients who have experienced failure of hormonal treatments. Because the putative cancer stem ...
tumor colonization biomarkers for cancer stem cells signaling pathways for cancer stem cells cancer differentiation and self-renewal cancer therapy targeting cancer stem cells drug delivery targeting cancer stem cells TME targeted therapy hypoxia targeted cancer therapy ...
Metastatic cancer stem cells: a new target for anti-cancer therapy? Over the past few years, supporting evidence for the cancer stem cell hypothesis has been provided for an increasing number of tumor entities. According to... PC Hermann,SL Huber,C Heeschen - 《Cell Cycle》 被引量: 171发表...
Colon cancer stem cells: implications for prevention and therapy The recent identification of colon cancer tumor-initiating cells adds further support to the cancer stem cell hypothesis. Ongoing basic and translational r... EH Huang,MS Wicha - 《Trends in Molecular Medicine》 被引量: 118发表: 20...
Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that contribute to tumor progression and therapy resistance. However, the underlying processes are still unclear. Elucidation of the key hallmarks and resistance mechanisms of CSCs may help improve patient outcomes and ...