Although immune checkpoint (IC) inhibition is a major treatment modality in cancer-immunotherapy, multiple cancers show low response. Our in-silico exploration by mining cancer datasets using R2, available clin
India:The Indian Council of Medical Research (ICMR) reported more than 14 lakh new cancer cases in India in 2023. The Indian government aims for an integrated approach for a “Cancer-free India,” encompassing prevention, screening, diagnosis, and treatment. The Union B...
Furthermore, the statistics indicate an increasing trend in BC cases. The situation in India reflects a similar scenario, as BC is the most prevalent cancer in the Indian population. According to the National Cancer Registry Programme Report 2020, released by the Indian Council of Medical Research...
According to the national data of National Cancer Registry Programme of the Indian Council of Medical Research (ICMR), India has reported 3.9 million cancer cases in 2016. The worst cancer affected states were Uttar Pradesh with 674,386 cases, followed by Maharashtra with 364,997 and Bihar with...
Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin, 71 (3) (2021), pp. 209-249, 10.3322/caac.21660 Google Scholar 6 V. Noronha, R. Pinninti, V.M. Patil, A. Joshi, K. Prabhash Lung cancer in the ...
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. Cancer J Clin. 2018;68(6):394–424. 5. Sabatini ME, Chiocca S. Human papillomavirus as a driver of head and neck cancers. Br J Cancer. 2020;122(3):306–14. 6. ...
The authors would like to thank the Vellore Institute of Technology, India authorities, for providing the necessary support in completing the manuscript. The authors acknowledge the Indian Council of Medical Research (ICMR), the Government of India agency, for the research grants (No. BMI/12(13)...
According to statistics, a BRCA1 mutation increases a woman's lifetime risk of breast cancer by 55–65 %. A BRCA2 mutation increases a woman's lifetime risk to 45 %(1). Breast cancer risk is also increased by mutations in PTEN, ATM, PALB2, CDH1, STK11, CHEK2, and TP53 [11]....
Varanasi population-based cancer registry The Varanasi PBCR was established in 2017, as a part of PBCRs operated by the Tata Memorial Centres (TMC). It provides representative statistics for cancer burden in the Uttar Pradesh state of Northern India, which is the most populous state of India ...
Despite recent advances in research, there are still critical lacunae in our basic understanding of the cause, pathogenesis, and natural history of many cancers, especially heterogeneity in patient response to drugs and mediators in the transition from m