et al. Evolution of systemic therapy for stages I–III non-metastatic non-small-cell lung cancer. Nat Rev Clin Oncol 18, 547–557 (2021). https://doi.org/10.1038/s41571-021-00501-4 Download citation Accepted10 March 2021 Published28 April 2021 Issue DateSeptember 2021 DOIhttps://doi.org...
The expression levels of TS, TP, and ERCC1, as determined by IHC, in cancer tissue were not significantly different in relapsed and non-relapsed patients. These expression levels were not different between stages. However, expression of TP and ERCC1 was significantly higher in cancerous tissue ...
Adjuvant chemotherapy for stages II, III and IV of colon cancer. Clin Transl Oncol. 2009;11(8):526–33. Article PubMed CAS Google Scholar Laurie JA, Moertel CG, Fleming TR, Wieand HS, Leigh JE, Rubin J, et al. Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of ...
Male breast cancer (MBC) comprises about 1% of all breast cancers but is found to be on the rise with the increasing incidence of female breast cancer [1]. The rarity of this condition precludes large randomized trials. Most of the information is therefore based on small single institution re...
From the laboratory to the bedside, different types of CD47-related drugs including mono-specific and BsAbs as well as fusion proteins have been developed into variable clinical research stages. Although IgG4 is the most popular isotype, however, other isotypes including IgG2 and IgG1 have been...
test was used to evaluate the statistical significance of the mRNA expression level in normal renal tissues versus tumor tissues. One-way ANOVA was used to compare MCL-1 expression among normal renal tissues versus different stages of RCC tumor tissues. The figure was performed using R version ...
肿瘤学家现在面临的选择是辅助化疗联合osimertinib(TKI)[4]或单独使用辅助TKI(如EVAN、adjuvant-CTONG 1104和EVIDENCE临床试验)[5-7]。在可切除的NSCLC中使用辅助化疗有明确的总生存(overall survival,OS)获益[8]。在最近更新的美国临床肿瘤学学会(American Society of Clinical Oncology,ASCO)的推荐指南中,以顺铂为...
survival rates sharply decline, particularly for advanced stages. In 2022, GLOBOCAN reported over 614,000 new bladder cancer cases and 220,600 deaths, with Europe leading in incidence rates, followed by Asia and North America. Other regions, including Africa, Latin America, and Oceania, report lo...
Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and is initially very responsive to platinum-based chemotherapy. However, the majority of patients relapse following initial surgery and chemotherapy, highlighting the urgent need to develop new therapeutic strategies. ...
R. et al. Fusobacterium nucleatum promotes colorectal cancer by inducing Wnt/β-catenin modulator annexin A1. EMBO Rep. 20, e47638 (2019). Article PubMed PubMed Central Google Scholar Flanagan, L. et al. Fusobacterium nucleatum associates with stages of colorectal neoplasia development, ...