Such gene therapy includes transferring genetic material into a host cell through viral (or bacterial) and non-viral vectors, immunomodulation of tumor cells or the host immune system, and manipulation of the tumor microenvironment, to reduce tumor vasculature or to increase tumor antigenicity for ...
PSMA is a transmembrane protein that is an attractive target for the detection and therapy of primary and metastatic prostate cancer. The expression level of PSMA is positively associated with tumor grade and risk of biochemical recurrence of prostate cancer.178PSMA functions like a cell surface rece...
A decade of immune-checkpoint inhibitors in cancer therapy Immunotherapy using immune-checkpoint modulators revolutionizes the oncology field far beyond their remarkable clinical efficacy in some patients. It creates radical changes in the evaluation of treatment efficacy and toxicity with a more holistic...
It was hypothesized that women receiving bright light therapy would exhibit more robust rhythms than women exposed to dim light. Thirty-nine women newly diagnosed with BC and scheduled for chemotherapy were randomized into 2 groups: bright white light (BWL) or dim red light (DRL). Women were ...
Sunlight was first used successfully as medication when children with deformed bones (rickets) were exposed to it, which corrected the deformity. They call it heliotherapy. To prevent osteoporosis, a gradual exposure to early-morning sunlight could be a natural way to increase calcium absorption int...
The CRISPR system is a revolutionary genome editing tool that has the potential to revolutionize the field of cancer research and therapy. The ability to precisely target and edit specific genetic mutations that drive the growth and spread of tumors has
A cancer-associated fibroblast gene signature predicts prognosis and therapy response in patients with pancreatic cancer. Front Oncol. 2022;12:1052132. Article PubMed PubMed Central CAS Google Scholar Shan T, Chen S, Chen X, Lin WR, Li W, Ma J, Wu T, Cui X, Ji H, Li Y, et al. ...
The field of oncology, nanotechnology, and biomedicine has witnessed rapid progress, leading to innovative developments in smart nanoparticles for safer and more effective cancer therapy. In this review, we will highlight recent advancements in smart nanoparticles, including polymeric nanoparticles, ...
radiotherapy or is in an advanced stage with laryngeal cartilage invasion (Stage T4) or laryngeal dysfunction [9]. Although the quality of life of patients with hypopharyngeal cancer has improved further with the increase of laryngeal function-preserving therapy, the survival rate has not improved ...
shape changes, bringing the two fluorescent proteins closer together. The researchers can detect whether this shift has occurred by shining green light onto the cells: If no hydrogen peroxide has been detected, the glow remains green; if hydrogen peroxide is present, the sensor glows red instead....