These tumours also had similar detection rates for EGFR mutations and for RET, ROS1, ALK and MET oncogenic isoforms compared with tumours in never-smokers, which suggests that they have a similar aetiology and pathogenesis. Large subclonal expansions were associated with positive subclonal selection...
a global study found an increase in the incidence of colorectal cancer in adults under 50 years of age in 19 out of the 36 countries examined, nine of which had a stable or declining pattern in older adults [7]. Although similar changes have been described in...
It is possible to cut back cancer mortality rates in men by promoting resistance training involving the most important muscle groups a minimum of two days per week,” the report said. “Becoming a bodybuilder is not a necessity,” Cancer Research UK Jessica Harris said. “Just half-hour of...
Anxiety and depression after cancer diagnosis: Prevalence rates by cancer type, gender, and age. J. Affect. Disord. 2012, 141, 343–351. [Google Scholar] [CrossRef] Smith, H.R. Depression in cancer patients: Pathogenesis, implications and treatment (Review). Oncol. Lett. 2015, 9, 1509–...
Ki-67 expression is related to cell proliferation, and higher protein levels are related to biological aggressiveness in BC [30,31]. The prognostic value of Ki-67 staining can be a useful tool for predicting survival and recurrence rates and, when associated with other markers, can also be ...
Worldwide, breast cancer is the most common cancer among women and the leading cause of cancer-related deaths in women [1]. Breast cancer rates do not begin to climb until after age 35 years and peak at age 70 years [2], yet there has been a growing recognition that environmental ...
“Rates of p16 (MTS) mutations in primary tumours with 9p loss”. Science 1994; 265:415–416. Article CAS Google Scholar Calleman CJ, Ehrenberg L; Jansson B; Osterman-Golkar S; Segerback D; Svensson K and Watchtmeister CA. “Monitoring and risk assessment by means of alkyl groups ...
According to a study, USP32 is highly expressed in small-cell lung cancer. The association between high levels of USP32 and low survival rates was significant. In vitro experiments confirm that USP32 promotes tumor growth. It is interesting to note that USP32 can influence the development of ...
in MSM is unclear but lower screening rates are well-documented within this population. Prostate cancer treatment affects urinary, bowel, and sexual function in both MSM and heterosexual men. These changes may have different sexual and psychological ramifications in MSM when compared to heterosexual ...
Two categories of dormancy in cancer can be distinguished. First, cellular dormancy, means that each cancer cell shows cell cycle arrest. The second is tumor dormancy when in cancer a balance between growth and apoptosis rates appears. The length of dormancy is long in prostate cancer or in ...