We then estimate the excess burden of somatic mutations in that genomic element above that expected for the background mutation rate, and cut the ranked mutations at this level. Mutations in each element with the highest driver ranking were then assigned as probable drivers; those below the ...
those who are in the 60–80th percentile of the risk distribution, which would be classified as a low-risk group for screening based on current incidence, would reach the risk threshold for screening at age 45 based on the increased incidences. If the incidence rate reaches that of Western...
This platform helps double the detection rate for high-risk esophageal lesions (1.8 percent) compared with that in the control group (0.9 percent), according to the study. Also, the real-time AI tool has shown a high sensitivity and specificity of 89.7 percent and 98.5 percent, respectively, ...
标题:NGS and FISH for MET amplification detection in post EGFR-TKI resistant non-small cell lung cancer (NSCLC) patients: a prospective, multi-center study in China 报告人:Qian Zheng——成都 09 摘要号:23P 标题:Clinical Impact and Prognostic Value of EGFR Mutation Co-occurring with ALK, ROS1...
There is still uncertainty on whether ionizing radiation from CT scans can increase the risks of cancer. This study aimed to identify the association of cumulative ionizing radiation from CT scans with pertaining cancer risks in adults. Five databases we
It is more likely that USP32 will be used as a possible biomarker and therapeutic target for gastric cancer because of the high expression of USP32 in this disease and its relationship to the short overall survival rate and high T stage of gastric cancer patients. The scientists discovered ...
While the US cancer death rates for the four most common cancers and cancer rates in general have decreased (National Cancer Institute, 2012), there has been a rise in cancer-related health disparities and less common cancers, such as melanoma, pancreatic, and renal cancer. In the follow-up...
While we confirm a lower TMPRSS2-ERG fusion-positive rate in tumours from African cases (10% versus 33%), novel African-specific PCa ETS family member and TMPRSS2 fusion partners were identified, including LINC01525, FBXO7, GTF3C2, NTNG1 and YPEL5. Notably, we found 74 somatic SV ...
Controlling the false discovery rate—a practical and powerful approach to multiple testing. J. R. Stat. Soc. Series B Stat. Methodol. 57, 289–300 (1995). Google Scholar Download references Acknowledgements We thank all of the individuals who took part in these studies, as well as all ...
(OR HM vs. Caucasian: 1.5, 95% CI: 1–2.2, BHp = 0.045; Hispanic vs. Caucasian: 2, 95% CI: 1.4–2.9). Similarly, a higher rate of younger HM and Hispanic women with BC was found in comparison to Caucasian patients (HM: 28%, Hispanic non-Mexican 39% and 17% in Caucasian...