Drug dosing and duration were based on prescribing information and pivotal trial publications.ResultsIn a hypothetical 10-million-member health plan, 503 and 723 patients were estimated to be treated with bevacizumab in year 1 and year 5, respectively. Assuming an annual market shift of 1.7%, ...
Percutaneous coronary intervention in patients with cancer and readmissions within 90 days for acutemyocardial infarction and bleeding in the USA readmissions within 90 days for acute myocardial infarction (AMI) and bleeding among patients with cancer who undergo percutaneous coronary intervention (PCI).....
Large numbers of elderly patients in the USA receive no treatment for esophageal cancer, despite evidence that multimodality treatment can increase survival. Our goal is to identify factors that may contribute to lack of treatment. Materials and Methods Using Surveillance Epidemiology and End Results (...
Researchers at the USA Health Mitchell Cancer Institute and the University of South Alabama College of Medicine uncovered a novel mechanism that underlies castration therapy resistance in metastatic prostate cancer. Their findings were published recently in the British Journal of Cancer. Patients whose can...
The cancer landscape of the USA is continually evolving owing to changing risk factor patterns and disease classifications, improvements in detection and treatment, and demographic changes, such as ageing and population growth. Monitoring the burden of c
patients in Phase 1 yielded a median PFS of 14.8 months and 95% confidence interval of 7.8–23 months, while nonparametric estimates yielded a median value of 15.4 months and 95% confidence interval of 5.4 months to “not reached.” Nonparametric analysis of a Phase 2 cohort of 60 patients ...
Esophageal Cancer Treatment Is Underutilized Among Elderly Patients in the USA 喜欢 0 阅读量: 11 作者:Stem,Miloslawa,Molena,Daniela,Lidor,O Anne,Blackford,L Amanda 摘要: Large numbers of elderly patients in the USA recei 关键词:Esophageal cancer Treatment Survival Disparities in care Elderly ...
Moreover, TUBB2B was one of 48 proteins exclusively found in exosomes of TNBC but not normal breast cells [12]. Higher TUBB2B expression in a subpopulation of endometrial cancer patients is associated with poorer prognosis [13]. Additionally, TUBB2B has been shown to promote HCC growth by ...
PRO completion is defined as the percentage of patients who were still considered on study and had an observed PRO at a specific time point [11]. We recorded whether a PRO instrument completion table was reported in the CSR and the definitions of the numerator and the denominator used for re...
As can be seen in the representative images shown in Fig. 2 the most marked immunoreactivity of all markers studied was in the carcinoma cells. AR and GR were observed in a predominantly nuclear localisation while aromatase, STS and 17βHSD2 were mostly cytoplasmic. The proportion of patients ...