Key factors associated with worse postoperative pain include higher ASA classification, advanced pTNM stage, and more than one chest tube in men and systematic lymph node dissection in women. Trial registration number: NCT03341377doi:10.1186/s12885-025-14191-zLiao, Jia...
The invention discloses a method for classification of cancer in an individual having contracted cancer. The method of classification involves the determination of microsatellite st
Among all the applicants, only patients who met the following 5 criteria were chosen to join in our study: patients had to (1) be over 18 years old; (2) have an American Society of Anesthesiologists (ASA) Physical Status Classification of II or III; (3) be scheduled to undergo a lapar...
Test is prognostic and estimates a probability (%) of BC recurrence in next 5 to10 years (late recurrence), as well as if a patient will benefit from an additional 5 years of hormonal therapy ("yes" or "no") [26,80]. The EndoPredict test® (Myriad Genetics, Inc.) is used to ...
3). Analysed at a per-patient level, this correlation held, even when considering tumours with similar purity and ploidy (Supplementary Fig. 3). Why such correlation should apply on a pan-cancer basis is unclear. It is likely that age has some role, as we observe a correlation between ...
whereas others are confined to a single cancer class. Certain signatures are associated with age of the patient at cancer diagnosis, known mutagenic exposures or defects in DNA maintenance, but many are of cryptic origin. In addition to these genome-wide mutational signatures, hypermutation localized...
7. To evaluate the occurrence of adenoma (low, intermediate and/or high grade intraepithelial neoplasia) at baseline and 12 months after randomization according to the Vienna classification of gastrointestinal epithelial neoplasia. In a patient subset additional analyses are planned with the following ...
detection of secretory products, either in the serum or using immunohistochemistry to assay the tumor cells, may be of relevance for classification (i.e., in the pituitary), for prognosis (such as in pancreatic insulinomas), or to correlate with the clinical symptoms in selected patient ...
IO patients will further examine the established classification model. A pan-therapy application of the Test with response prediction across tumor types with historically low objective response rates (ORRs) could aid in improving both patient outcomes and increase the cost-effectiveness of cancer care....
created from two clonal metastases from the same patient. We find that SVclone’s performance is comparable to single-nucleotide variant-based methods, despite having an order of magnitude fewer data points. As part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) consortium, which aggregated...