Figure 2.The endothelial and vascular bone marrow niches. The endosteal niche is quiescent and sustains dormant HSCs long term. The vascular niche maintains the self-renewal pool by asymmetric division and produces multipotent progenitors. HSCs remain in the niches in a quiescent state (G0of the ...
A couple types of cancer can grow in your bones. Primary bone cancer is cancer that starts in the cells of your bones. This type is rare; only about 1% of all cancers are primary bone cancer. More often, cancer in your bones starts in other cells of your body and spreads to your bo...
Thus, leukemia refers to a cancerous proliferation of white blood cells (leukocytes). Cancerous tumors that arise in lymphoid organs, such as the spleen, the thymus, or the lymph glands, are described as malignant lymphomas. The term lymphoma is often used without the qualifier malignant to ...
Long term medical costs of post-menopausal breast cancer therapy [abstract]. 36th Proc Am Soc Clin Oncol 2000 May 20; 19: 446Cocquyt V, Moeremans K, Annemans L, Clarys P, Van Belle S. Long-term medical costs of postmenopausal breast cancer therapy. Ann Oncol 2003; 14:1057-1063....
et al. Prognostic value of disseminated tumor cells in the bone marrow of patients with operable primary breast cancer: a long-term follow-up study. Ann. Surg. Oncol. 20, 1865–1871 (2013). Article PubMed Google Scholar Boyle, W. J., Simonet, W. S. & Lacey, D. L. Osteoclast ...
As one of the most common metastatic sites of malignancies, bone has a unique microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated capillaries in the bone, bone matrix, and bone cells, including osteoblasts and osteoc
When Yelak Biru was diagnosed with stage 3 multiple myeloma in 1995, his prospects looked grim. The antibody-producing immune cells in his bone marrow were growing out of control and had lodged in several of his bones. He was a newly married graduate student, just 25 years old. The diseas...
Bone is the most frequent destination of metastatic breast cancer cells and is also the most common site of first distant relapse of breast cancer.12,13Breast cancer cells that spread to the bone form bone metastases or reside in bone marrow as dormant disseminated tumor cells (DTCs) or micro...
The medical term for lung cancer is lung carcinoma. There are two main types of lung cancer, small-cell lung carcinoma, and non-small-cell lung...Become a member and unlock all Study Answers Start today. Try it now Create an account Ask a question Our experts can answer your tough ...
(in the value-neutral sense of being negatively charged), feminine sign ruled by the Moon. Its symbol is the crab, and its glyph is said to represent the two claws of a crab. A moody sign, Cancer is the source of the term “crabby.” Cancer is associated with the breasts and the ...