Figure 2.The endothelial and vascular bone marrow niches. The endosteal niche is quiescent and sustains dormant HSCs long term. The vascular niche maintains the self-renewal pool by asymmetric division and produces multipotent progenitors. HSCs remain in the niches in a quiescent state (G0of the ...
(redirected fromBone-marrow cancer) Dictionary Thesaurus Medical Cancer , in astronomy Cancer[Lat.,=the crab], in astronomy,constellationlying on theecliptic(the sun's apparent path through the heavens) between Gemini and Leo; it is a constellation of thezodiac. It contains the star clusterPraese...
whereas in other cases it is based on the tumor’s microscopic architectural pattern or gross appearance. The termadenoma, for instance, designates a benign epithelial tumor that either arises in endocrine glands or forms a glandular structure. Tumors of the ovarianepitheliumthat contain largecystsare...
in fat and high in vegetables, fruits, and grains over the course of years and are diagnosed with breast cancer have a reduced risk of dying from the disease. Long-term dietary changes can significantly benefit survival among women with breast cancer who exhibit characteristics ofmetabolic ...
Cervical cancer is the term used to define the malignant neoplasm that arises from the cells of the uterine cervix, invading the female reproductive system. From: European Journal of Pharmacology, 2022 About this pageSet alert Also in subject area: Nursing and Health ProfessionsDiscover other to...
As one of the most common metastatic sites of malignancies, bone has a unique microenvironment that allows metastatic tumor cells to grow and flourish. The fenestrated capillaries in the bone, bone matrix, and bone cells, including osteoblasts and osteoc
In the case of tumor cells which can express typical markers for both cell states (epithelial and mesenchymal), the term transformation was replaced with transition [82]. Decades of studies have revealed that cancer cells are able to form not only fully epithelial or fully mesenchymal cancer ...
Bone cancer is when cells in your bones grow out of control. Usually, when you have bone cancer, it comes from another cancer that has spread to your bones or metastatic bone cancer. But sometimes, the cancer cells start in your bones. In that case, it's called primary bone cancer. Pr...
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Primary tumours activate granulopoiesis in the bone marrow and actively stimulate the release and recruitment of both mature neutrophils and their progenitors. Depending on the spectrum and quantity of soluble mediators produced by cancer cells and cancer-associated cells, neutrophils can be polarized into...