The German physician Rudolf Virchow observed greatly increased numbers of white blood cells in the blood smear of one of his patients, and coined the term leukemia (meaning “white blood”) to describe this phenomenon. Clinicians of the day subsequently reported that although leukemia was rare, ...
Furthermore, the model trained from microarray data can also be applied to RNA-seq data, highlighting the clinical relevance of relative gene expression levels in blood. 此外,从微阵列数据训练的模型也可以应用于RNA-seq数据,突出了血液中相对基因表达水平的临床相关性。 Gene regulatory networks—and conse...
Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: a longitudinal, nested case-control study in the Nordic coun... Vitamin D inhibits the development and growth of prostate cancer cells. Epidemiologic results on serum vitamin D levels and prostate ...
Gliocidin can target brain tumours by disrupting the production of nucleotides needed for cell growth. The molecule’s unusual ability to cross the blood–brain barrier suggests a promising way to develop therapies. Mushtaq A. Nengroo &Issam Ben-Sahra ...
To the best of our knowledge, the prognostic value of fasting blood glucose (FBG) has never been studied in patients with ENKTL. In our pilot study, we observed that patients with higher FBG levels had worse outcomes in clinical practice. The objective of this retrospective analysis was to ...
Fat biomolecules in the blood, called 'serum lipids,' are necessary evils. They play important roles in the lipid metabolism and are integral for the normal functioning of the body. However, they have a darker side; according to several studies, they are
2006. Blood lead levels and death from all causes, cardiovascular disease, and cancer: results from the NHANES III mortality study. Environ Health Perspect 114:1538-1541.Schober SE, Mirel LB, Graaubard BI, Brody DJ, Flegal KM. Blood lead levels and death from all causes, cardiovascular ...
Authors sought to assess the association of prostate cancer risk with blood levels of omega-3 polyunsaturated fatty acids (n-3 PUFA) through a meta-analysis of human epidemiological studies in available online databases (July, 2012). After critical appraisal by two independent reviewers, Newcastle-...
This study aimed to investigate if high levels of blood cadmium at baseline were associated with increased fracture risk during follow-up in middle-aged women. No increased fracture risk was observed during follow-up, but women with higher levels of cadmium had an increased overall mortality. Expo...
In a phase 1 trial followed by translational analyses, patients with acute myeloid leukemia (AML) treated with chimeric antigen receptor (CAR) T cell therapy targeting CD123 experienced high levels of cytokine release syndrome and short-lived clinical responses, probably due to CAR T cell-derived ...