Problems in cancer surveillance: delineating in situ and invasive bladder cancer. In this issue of the Journal, Lynch et al (7) describe the implications of combining in situ and invasive bladder cancers for reporting purposes by the Sur......
Neither lifetime recreational nor strenuous occupational physical activity appeared to be associated with risk of breast carcinoma in situ. In contrast, recreational physical activity was associated with a reduced risk of invasive breast cancer. After adjustment for potentially confounding factors, women ...
W. et al. Collagen alignment as a predictor of recurrence after ductal carcinoma in situ. Cancer Epidemiol. Biomarkers Prev. 27, 138–145 (2018). Article CAS PubMed Google Scholar Mayorca-Guiliani, A. E. et al. ISDoT: in situ decellularization of tissues for high-resolution imaging and...
Upon antigen recognition of CART cells at the tumor site, CART cells proliferate and induce an in situ inflammatory cytokine cascade in the tumor microenvironment resulting in direct and indirect mechanisms of tumor killing. CART cells secrete perforin, granzymes, granulocyte macrophage-colony ...
Most cancers can be classified according to the stage of disease, a measure of how widely it has spread in the primary organ and beyond: stage 0 (i.e., in situ), I, II, III and IV. Localized disease refers to cancer that is contained where it started with no sign of spreading (St...
Schematic depiction of an in situ DC vaccine using chimeric cross-linked polymersomes (CCPS) as adjuvants combined with PDT and ICD for the treatment of MC38 colorectal cancer.aProcess of self-assembled nanoparticle formation.bImmune response in vivo after injection of CCPS/HPPH/DOX. Reprinted wit...
Schematic depiction of an in situ DC vaccine using chimeric cross-linked polymersomes (CCPS) as adjuvants combined with PDT and ICD for the treatment of MC38 colorectal cancer.aProcess of self-assembled nanoparticle formation.bImmune response in vivo after injection of CCPS/HPPH/DOX. Reprinted wit...
cancers Article Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer Carter J Barger 1, Connor Branick 1, Linda Chee 1 and Adam R. Karpf 1,2,* 1 Eppley Institute for Cancer Research, University of Nebraska Medical Center, Omaha, NE 68198, USA; c...
Molecular subtypes in ductal carcinoma in situ of the breast and their relation to prognosis: a population-based cohort study Background Different molecular subtypes of breast cancer have been identified based on gene expression profiling. Treatment suggestions based on an approxi... W Zhou,K Jirst...
in situ, invasive cancer and lymph node metastasis—it is notable that virtually every sample exhibited a spatial organization of clones, which warrants further investigation in larger cohorts. The fact that nearly all clones examined in this dataset displayed distinct clone-specific gene expression, ...