We retrospectively reviewed the outcome in our patients with prostate cancer and regional positive lymph nodes who underwent prostatectomy. Between January 1984 and December 2002, 147 men were found to have local lymph node metastases after surgery, of whom 135 underwent further androgen ablation, incl...
Lymph node dissection performed during radical prostatectomy is the gold standard for determining lymph node invasion (LNI) in patients with prostate cancer. The role of pelvic lymph node dissection in patients with low-, intermediate-, and high-risk pro
Superparamagnetic nanoparticles of iron oxide (SPION) were shown to be non-inferior to standard radioisotope tracer in breast cancer and may be used as an alternative to identify sentinel lymph nodes (SLN). The aim of this study was to assess the feasibility of sentinel lymph node dissection (...
More than 40% of men with intermediate-risk or high-risk prostate cancer will experience a biochemical recurrence after radical prostatectomy. Clinical guidelines for the management of these patients largely focus on the use of salvage radiotherapy with or without systemic therapy. However, not all ...
Lymph node metastasis (LNM) in many solid cancers is a well-known prognostic factor; however, it has been debated whether regional LNM simply reflects tumor aggressiveness or is a source for further tumor dissemination. Similarly, the metastatic process in head and neck cancer (HNC) has not bee...
Surgery may be needed, depending on the stage of the cancer. Part or all of your prostate may be removed. You may also need to have some lymph nodes taken out. This may help keep the cancer from spreading to other parts of your body. Your healthcare provider may recommend a combination...
Intraoperative search for sentinel lymph nodes by γ-probe in open and laparoscopic surgery is possible. Routine use of choline PET/CT for initial staging of prostate cancer is not yet recommended. MRI combined with ultrasmall particles of iron oxide (USPIO) permits differentiation with a very ...
Prostate cancer (PCa) nodal staging does not account for tumor burden within the lymph nodes (LNs). In this retrospective single institution/single surgeon study, we assessed the significance of LN tumor burden in pN1 PCa patients after undergoing robotic-assisted radical prostatectomy with extended...
Nerve pain. If prostate cancer presses on a nerve in your body, you can feel this type of pain. The feeling can be described as shooting, burning, or tingling. Nerve pain can also cause an area to feel numb. Lymphedema.If your prostate cancer spreads to your lymph nodes, it can cause...
after using conventional treatments (surgery, chemotherapy, etc.) mostly contributed by vicious cancer stem cells (CSCs) [7,8]. Advanced and more potent chemotherapeutic drugs have been able to succeed the previously available anticancer drugs individually or chronologically or in combination with ...