evaluating intracerebroventricular B7-H3-targeting CAR T cells in children and young adults with diffuse intrinsic pontine glioma, repeated intracranial infusions were feasible and well tolerated with a median overall survival of 19.8 months and 3 patients surviving over 40 months from diagnosis....
Distinct clinicopathological features and treatment differences in breast cancer patients of young age Rasmus O. C. Humlevik ,Amalie A. Svanøe &Erling A. Hoivik Article 15 February 2025|Open Access METTL14 suppresses the migration and invasion of hepatocellular carcinoma cells by m6A methylation ...
Multilevel and multivariate logistic regression models were used to evaluate the disparities in ovarian cancer diagnosis and treatment adjusting for age, tumor pathological characteristics, marital status, insurance status, rural residency, county level socioeconomic characteristics, and year of diagnosis....
"The disparity in deaths likely reflects systemic and preventable barriers to getting quality care. Whether it's screening for cancer, timely diagnosis, or the receipt of proven treatments," Lawrence explained. "Black individuals continue to have a delay in care or receive poorer care than their ...
Furthermore, 33 of the included studies conducted the multivariate analysis. Most of the included variables used to adjust the multivariate analysis were the commonly reported biomarkers (ER, PR, HER2, and Ki-67), age, tumour size and grade, age at diagnosis, lymph node stage, histological gra...
The rapid increase in CRC trends among the Black population group is concerning and requires further investigation and increased efforts for cancer prevention, early screening and diagnosis, as well as better access to cancer treatment. 展开 关键词: Colorectal cancer Incidence Mortality South Africa ...
Total prevalence is partitioned into 4 sequelae: (1) diagnosis/treatment, (2) remission, (3) metastatic/disseminated, and (4) terminal phase. Each sequela prevalence is multiplied by a disability weight to estimate YLDs. Lifetime prevalence of procedure-related disability is estimated for larynx...
Here we intensively sequence 682 micro-scale oesophageal samples and show, in physiologically normal oesophageal epithelia, the progressive age-related expansion of clones that carry mutations in driver genes (predominantly NOTCH1), which is substantially accelerated by alcohol consumption and by smoking....
Prostate cancer and its treatment frequently lead to sexual side effects that negatively impact personal identity, sexual function, and intimate relationships. The sexual consequences of prostate cancer treatment on men who have sex with men (MSM) differ
Assuming a 10-year latency period between exposure and cancer diagnosis (appendix p 2), alcohol consumption estimates for 2010 were obtained from the Global Information System on Alcohol and Health as adult per capita alcohol consumption in litres of alcohol per year by country disaggregated by age...