, in Pharmacological Research, 2017 1.2 Small cell lung cancer The main forms of lung cancer include small cell lung cancer (SCLC) [3] and non-small cell lung cancer (NSCLC) [2]. Small cell lung cancer is an aggressive disease that accounts for 10–15% of all lung cancers. Meta...
Case 11: PET and Bone Scans in Non-Small Cell Lung Cancerdoi:10.1007/978-3-031-09737-9_11PET and bone scan are complimentary in non-small cell lung cancer (NSCLC) with EGFR.Wong, Ching Yee OliverSutter Health ImagingWu, DafangNorthern California PET Imaging Center...
Integrating genetic subtypes with PET scan monitoring to predict outcome in diffuse large B-cell lymphoma The prognostic impact of genetic subtypes in diffuse large B-cell lymphoma not otherwise specified (DLBCL-NOS) remains unclear. Here, the authors use data from multiple clinical trials to identif...
PET scan. The doctor injects a radioactive substance called a tracer into your arm. It travels through your body and gets absorbed into the cancer cells. Together with a CT scan, this test can help find cancer in lymph nodes and other areas. ...
]. Mavragani et al. found that DNA damage from low radiation doses was not severe enough to cause cell death, but could trigger a red flag [65, 66]. One of those red flags is the body’s immune system. Increasing evidence suggests that radiation exposure of low dose may not only ...
In addition to mutations seen in tumor tissue, cancer patients have cell-free DNA originating from cancer cell lysis/death or active secretion, which is referred to as circulating tumor DNA (ctDNA). It can be found in body fluids such as blood, urine, stool, saliva, sputum, and exhaled ...
(PET 1 um) using the same cell number. Inserts were transferred to multi-well plates after a 24 h preincubation period. All experiments were performed after 72 h of cocultivation. ASCs maintained under standard conditions served as a control. Alternatively, they were cultured for 72 h in ...
PET scan: A small amount of radioactive material is injected into the bloodstream and is taken up by cells that are very active, like cancer cells. This helps show where the cancer has spread. Video-assisted thoracoscopy (VATS): A doctor will insert a lighted tube with a video camera thro...
in neuroendocrine cells, the progenitor cell type of SCLC, and has been identified to be overexpressed in the majority of SCLCs30. As expected, a subset of the genes with ASCL1 binding sites were differentially expressed between SCLC and NSCLC (Fig.5b). Given the reported differences in ...
2.1. The pH evaluation as a hallmark in cancer detection The pH measurement results demonstrated that in tumor cells, the extracellular environment has a more acidic pH than normal cells, but cytosol has a similar pH in both cell types [8]. Extracellular pH (pHe) evaluated in normal cells ...