IN extending our recently published work on cell growth and the development of tumours 1 , we have observed that in the livers of rats fed 2-acetylamino-fluorene the cell proliferation continues at a constant rate during the pre-cancerous period arid does not decrease as we had at first ...
We found that CSCs did not follow the common pattern of a typical growth curve of mammalian cells in contrast to the cancer cell lines. This observation of rapidly growing CSCs indicates their involvement in tumor formation. 展开 关键词: Cancer stem cellgrowth curve Nanog Oct3/4 Sox2 ...
The interplay of positive and negative interactions between drug-sensitive and resistant cells influences the effectiveness of treatment in heterogeneous cancer cell populations. Here, we study interactions between estrogen receptor-positive breast cance
n = 2) and RKO (e,n = 3) cells. Bar graphs show the colony numbers per dish. Error bars represent SD.f,gGrowth curves of WT,Pum1−/−orPum2−/−HCT116 (f,n = 4) and RKO (g,n = 3) cells. Error bars represent SD.h,iCell doubling time...
Lastly, analysis of single-cell data from cell lines reveals the presence of Prol-phenotype subpopulations in both Metab-subtype and EMT-subtype cell lines, further confirming that the Prol-phenotype represents cells in a proliferative state. The definition of Prol-phenotype clarified the ...
IN extending our recently published work on cell growth and the development of tumours 1 , we have observed that in the livers of rats fed 2-acetylamino-fluorene the cell proliferation continues at a constant rate during the pre-cancerous period arid does not decrease as we had at first sup...
To examine the long term impact of miR-206 on cell growth and colony formation, we generated a stable line of SGC-7901 cells, P2GM-miR-206, that expresses miR-206 from a constitutively active vector, MSCV-P2GM, and a line of empty vector-carrying cells, P2GM-miRctrl. First, we exami...
The mechanism of epidermal hyperpigmentation in cafe-au-lait macules of neurofibromatosis type 1 (von Recklinghausen's disease) may be associated with dermal fibroblast-derived stem cell factor and hepatocyte growth factor Br. J. Dermatol, 148 (2003), pp. 689-697 View in ScopusGoogle Scholar 36...
APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell-Mediated Antitumor Immune Responses. Cancer Immunol Res. 2022;10:70–86. Article CAS PubMed Google Scholar Fokas E, Prevo R, Hammond EM, Brunner TB, McKenna WG, Muschel RJ. Targeting ATR in DNA damage response and ...
Other reports showed that miR-199a suppressed cell growth in renal cancer [9] and inhibited cell proliferation in human Hepatocellular carcinoma (HCC) [10]. Huang et al. also found that miR-199a-5p was significantly down-regulated in advanced stage in small cell carcinoma of the cervix (...