2022年40卷3期 这幅图片显示了非小细胞肺癌(Non-Small-Cell Lung Cancer, NSCLC)中成熟三级淋巴样结构(Lypphoid Structure, TLS),描绘的是一项关于浆细胞、TLS和PD-L1抑制剂获益相关性的研究[1]。 研究者对2项大型临床研究中接受PD-L1抑...
Cancer Cell International is an open access, peer-reviewed, online journal that considers research on cancer cells, originating largely from work using cell culture techniques. It serves the world as a publication of the International Federation for Cell Biology. Much of cancer work relates to biolo...
2.5 Functional single-cell analyses to study the interactions between stromal fibroblasts, tumour cells and other cell types in the microenvironment As mentioned in the previous section, single-cell analyses may serve as valuable tools to understand the crosstalk between cancer cells and other cellular...
2022年9月8日,中国医学科学院北京协和医学院/海军医科大学/南开大学曹雪涛及海军军医大学张迁共同通讯在Cancer Cell(IF=39)在线发表题为“Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance”的研究论文,该研究表明M2 样 TAM 具有最...
Volume 40, Issue 6, 13 June 2022, Pages 656-673.e7ArticleMesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer Author links open overlay panelHuocong Huang 1 2 11, Zhaoning Wang 7, Yuqing Zhang 2 3 9, Rachana N. ...
最近,空间转录组的方法绘制了CRC的形态特征【7】,揭示了肿瘤-TIME 的共同进化【8】,并解析了CRC的分子异质性【9】。然而,决定TIME和治疗响应的因素在很大程度上仍未知。 近日,来自英国弗朗西斯·克里克研究所的Francesca D. Ciccarelli研究团队在Cancer Cell上发表题为A constitutive interferon-high immunophenotype ...
另外,2022年9月8日,中国医学科学院北京协和医学院/海军医科大学/南开大学曹雪涛及海军军医大学张迁共同通讯在Cancer Cell(IF=39)在线发表题为“Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to prom...
New cryo-EM cancer cell research may help combat leukemia Over the past year, cryo-EM also helped toadvance our understanding of leukemia. Acute myeloid leukemia (AML), a cancer that starts in the bone marrow and moves quickly into a person’s blood, isone of the most common types of le...
另外,2022年9月8日,中国医学科学院北京协和医学院/海军医科大学/南开大学曹雪涛及海军军医大学张迁共同通讯在Cancer Cell(IF=39)在线发表题为“Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance”的研究论文,该研究报告了促肿瘤 TAM...
Received20 May 2021 Accepted22 June 2022 Published05 August 2022 Issue DateAugust 2022 DOIhttps://doi.org/10.1038/s41588-022-01141-9 Subjects Cancer Cancer microenvironment Mapping the cancer cell states conserved across solid tumors Daniel Roden ...