the mortality in NSCLC remains high1,2. Recently, immunotherapies, particularly those targeting the PD-1/PDL-1 axis, have offered significant improvements in overall survival for a subset of patients with NSCLC2. However, a majority (>75%) of patients experience little clinical benefit3d...
Brewer, G. J. Anticopper therapy against cancer and diseases of inflammation and fibrosis. Drug Disco. Today 10, 1103–1109 (2005). CAS Google Scholar Saha, B., Mukherjee, A., Samanta, S., Paul, S., Bhattacharya, D., Santra, C. R. et al. A novel Cu(ii)–mal–picoline complex...
Heatmaps were made using the Pheatmap (version 1.0.12) and RColorBrewer (version 1.1-2) packages, and the Venny web portal (version 2.1) was used to make all Venn diagrams. Differential gene expression (DGE) was performed on non-normalized counts using the standard DESeq2 package (version...