If detected early, both types of cancer can be effectively treated and at lower medical costs. As such, the World Health Organization (WHO) launched a global strategy in 2020 to accelerate the elimination of cervical cancer and set a 90-70-90 target to be achieved by 2030, that is, to ...
N. et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. J. Clin. Oncol. 33, 540–549 (2015). Article CAS PubMed Google Scholar Porter, D. L. et...
The prodrug gliocidin effectively kills glioblastoma cells by targeting de novo purine synthesis, improving survival in mouse models. Yu-Jung Chen , Swathi V. Iyer & Luis F. Parada News & Views | 20 November 2024 Brain-penetrating molecule might offer a route to treat glioblastoma tumours ...
One defining feature of cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs; the latter process is referred to as metastasis. Widespread metastases are the primary cause of death...
Examples of coherent beams produced by cancer cells. Enlarged and slightly contrasted parts of fingertip coronas are shown next to the raw BHT-grams. A – gastrointestinal cancer, ongoing radiation therapy; B – non-treated renal cancer with spreading metastasis. White arrows point to the sca...
Furthermore, the combination approach effectively inhibited the PI3K/Akt/mTOR signaling pathway, reversed EMT, and decreased CSC marker expression [125]. In liver cancer, the use of curcumin (NF-kB signaling pathway inhibitor) to block NF-kB can specifically target the CSC population, and ...
Unifocal PTMC tumors with diameters equal to or below 0.5 cm in some individuals may be treated less aggressively; a hemithyroidectomy with isthmectomy is an acceptable procedure. Our study helps clinicians to more safely and effectively select patients for whom aggressive treatment is ...
(Oncotype Dx, Prosigna, EndoPredict/EPclin, GGI, MammaPrint, breast cancer index, etc.), which is used by patients with hormonal positive receptors who can be treated surgically and hormonally without systemic chemotherapy. The third level is tertiary risk prediction such as adjuvant chemotherapy and...
(20.1 per 100,000 women per year), breast cancer is the most prevalent cancer in females. Statistically, 95% of breast cancer are categorized as adenocarcinomas, and 55% of all patients may go into invasive phases; however, it can be successfully treated in approximately 70–80% of cases ...
it can be effectively prevented as this heating typically occurs in the immediate vicinity of the electrodes and when too much energy is applied too quickly18. A previous study also reported that the temperature rise around the electrodes did not exceed the threshold if the electric pulses were ...