This chapter highlights the existing research linking the environment, blood-derived DNA methylation alterations, and cancer risk, and points out how these epigenetic alterations may be contributing fundamentally to carcinogenesis. 展开 关键词: Animals Humans Environmental Pollutants Genetic Markers Tumor ...
Since the cancer stem cell concept has been widely accepted, several strategies have been proposed to attack cancer stem cells (CSC). Accordingly, stem cell markers are now preferred therapeutic targets. However, the problem of tumor specificity has not
Breast cancer treatment can induce alterations in blood- and neuroimaging-based markers. However, an overview of the predictive value of these markers for cognition is lacking for breast cancer survivors. This systematic review summarized studies of the last decade, using the PubMed database, evaluat...
4th Workshop on Blood Markers in Breast Cancer Milan 28th September 1998doi:10.1177/172460089901400101J.F.R. RobertsonE. BombardieriM. GionSAGE PublicationsThe International Journal of Biological Markers
In the era of personalized medicine, traditional prognostic markers, such as lymph node metastasis, tumor size and histological tumor grade are no longer sufficient to guide early-diagnosed BC patients [4]. Recent technology advances improved our understanding of the molecular basis of tumor progressio...
New markers may also contribute to progress in personalized medicine, providing opportunities for women to be counseled about treatment choices.113 Given the common agreement that women should know what to expect when undergoing breast cancer screening, there is a need for more research on ...
The tumour microenvironment, also termed the tumour stroma or tumour mesenchyme, includes fibroblasts, immune cells, blood vessels and the extracellular matrix and substantially influences the initiation, growth and dissemination of gastrointestinal canc
Progress in understanding the complexity of a devastating disease such as cancer has underscored the need for developing comprehensive panels of molecular markers for early disease detection and precision medicine applications. The present study was conducted to assess whether a cohesive biological context ...
MicroRNA-200 as potential diagnostic markers for colorectal cancer: meta-analysis and experimental validation. Cell Mol Biol (Noisy-le-grand). 2018;64(6):77-85. doi:10.14715/cmb/2018.64.6.14PubMedGoogle ScholarCrossref 281. Usher-Smith JA, Harshfield A, Saunders CL, et al...
Gastric cancer stem cells: evidence, potential markers, and clinical implications. J. Gastroenterol. 51, 313–326 (2016). Article CAS PubMed Google Scholar Irollo, E. & Pirozzi, G. CD133: to be or not to be, is this the real question? Am. J. Transl. Res. 5, 563–581 (2013)....