Objective: Hydrogel spacers have a novel role in the treatment of low- and intermediate-risk prostate cancer with dose-escalated radiation therapy. Given the growing number of patients undergoing treatment with radiation therapy, the use of hydrogel spacers is expected to increase. The purpose of ...
without ED (7.9 months versus 15.5 months, hazard ratio 1.73, 95% confidence interval 1.23 to 2.43,P = 0.002). On the secondary endpoint analysis, ED was associated with lower objective response rate (46.8% versus 62.1%, odds ratio 0.54,P = 0.022), reduced 2-year overall...
a cell state that persists despite exposure and resistance to ENZ. Karthaus et al. recently identified activated luminal prostate cells able to regenerate the epithelium following castration30. We extracted the gene expression profile associated with these prostate luminal cells (see “Methods”) and u...
. Because if I were to say, okay, I’m going to put you on sipuleucel-T, or abiraterone, or enzalutamide, who would win in that decision? So that’s why with the absence of PSA declines, when you get sipuleucel-T, smart people have thought about, well, how are we going to circum...
Circumcision unlikely to be associated with prostate cancer risk A letter to the editor is presented in response to the article related to circumcision for reducing the relative risk of prostate cancer (PCa) in a previou... Grulich, Andrew E.,Vajdic, Claire M. - Cancer (0008543X) 被引量...
aIn the case of the 67-year old pensioner with prostate cancer, associated with severe lumbar pain, metastases were excluded with great certainty. Orthopedic treatment in the form of injections, infusions and medication was rather unsuccessful. Periradicular therapy carried out by a radiologist under...
Low androgen levels in men are associated with increased cardiovascular risk, through unclear mechanisms. We measured arterial stiffness (''compliance'') in 21 men receiving complete testosterone suppression therapy for prostate cancer, and in 25 controls. Systemic arterial compliance (SAC), which asses...
Obesity– It has been clearly shown that obesity is associated with increased risk for death from prostate cancer. Thus, the simplest advice for avoiding death from prostate cancer is to prevent obesity and if you are obese, to lose weight and keep it off. ...
Prostate RT was associated with greater overall and failure-free survival in patients with only nonregional lymph node metastasis (M1a) or 3 or fewer bone metastases without visceral metastasis. Meaning In patients with prostate cancer, bone metastatic burden and metastasis location may be useful in...
A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer The PSA (KLK3) genetic variant rs17632542 is associated with reduced prostate cancer risk and lower serum PSA levels, although the underlying reasons are unclear. Here, the authors show that this PSA va...