Cancer is a disease characterized by the uncontrolled multiplication of abnormal cells in the body. There are numerous types of cancers, with certain types being major causes of sickness and death worldwide.
MAF amplification increases the risk of breast cancer (BCa) metastasis through mechanisms that are still poorly understood yet have important clinical implications. Oestrogen-receptor-positive (ER+) BCa requires oestrogen for both growth and metastasis,
Pancreatic cancer (PC) is one of the most aggressive recalcitrant malignancies and portends a high mortality rate [1]. Based on the National Cancer Institute 2021 estimates, PC accounts for 3.2% of all new cancer cases and 7.9% of all cancer-related deaths [2]. In contrast to the steady ...
“Phoenix Paradigm” was proposed by researchers of the Pittsburgh Cancer Institute: their experiments with the Kaposi Sarcoma-associated Herpesvirus resulted in the conclusion that excessive cell death, rather than its absence, may be a defining force that drives the cancer emergence [82]. In ...
By 2012 it had surpassed breast cancer as the leading cause of cancer death among women in developed countries. The rapid increase in the worldwide prevalence of lung cancer was attributed mostly to the increased use of cigarettes following World War I, though increases in environmental air ...
Importance Colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52 980 persons in the US projected to die of colorectal cancer in 2021.1 Colorectal cancer is most frequently diagnosed among persons aged 65 to 74 years.2 It is estimated tha...
Because there are no early signs, gastric cancer is often diagnosed very late. Around 50% of cancers have already reached an advanced stage that does not allow for curative treatment due to tissue invasion andmetastases.[33] If diagnosed at a very early stage, the5-yearsurvival rate is 95%...
Since cancer of the pancreas is now the fourth most common cause of death from cancer in the United States, and since the signs and symptoms of this disease are such poor indicators of its presence, other more effective diagnostic methods must be utilized in an attempt to lower the mortality...
Volk, PhD JAMA Network Open Conversations with Dr Bauchner (28:17) USPSTF Recommendation—Screening for Lung Cancer 1x 0:00 / 0:00 Subscribe to Podcast Abstract Importance Lung cancer is the second most common cancer and the leading cause of cancer death in the US. In 2020, an estimated ...
Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the form of cell death that can be regulated by a variety of biomacromolecules, which is distinctive from accidental cell death (ACD). Accumulating evidence has reveale